Er, Yi Xian and Lee, Soo Ching and Than, Leslie Thian-Lung and Muslim, Azdayanti and Leong, Kin Fon and Kwan, Zhenli and Mohd Sayed, Izandis and Lim, Yvonne Ai-Lian (2022) Tinea Imbricata among the indigenous communities: Current global epidemiology and research gaps associated with host genetics and skin microbiota. Journal of Fungi, 8 (2). ISSN 2309-608X, DOI https://doi.org/10.3390/jof8020202. (In Press)
Full text not available from this repository.Abstract
Tinea imbricata is a unique fungal skin disease that mostly affects indigenous populations in Southeast Asia, Oceania, and Central and South America. The control and management of this disease among these communities are challenging given their remote locations, certain traditional practices, and severe malnutrition status. To date, there are only a handful of reports published globally, which highlights the need for a more holistic approach in addressing this skin disease. Several bodies of evidence and reports have shown that host genetic factors have a profound influence on the pathogenesis of tinea imbricata, while skin microbiota is touted to have a role in the pathogenesis of the disease. However, there are limited studies of how host genetics and skin microbiota impact disease susceptibility in the host. To improve the understanding of this disease and to find possible long-term effective treatment among the affected indigenous communities, a comprehensive literature review is needed. Hence, this review paper aims to present the current status of tinea imbricata among the indigenous communities, together with published findings on the possible underlying reasons for its specific distribution among these communities, particularly on the ways in which host skin microbiota and host genetics affect occurrence and disease patterns. This information provides valuable insights for future research by highlighting the current knowledge gaps in these areas.
| Item Type: | Article |
|---|---|
| Funders: | Ministry of Higher Education, Malaysia through the Fundamental Research Grant Scheme (FRGS) [Grant No: FRGS/1/2021/SKK06/UM/01/1 (FP017-2021)] |
| Uncontrolled Keywords: | Tinea imbricata; Trichophyton concentricum; Epidemiology; Human genetics; Skin microbiota |
| Subjects: | Q Science > QR Microbiology |
| Divisions: | Faculty of Medicine |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 21 Aug 2022 03:56 |
| Last Modified: | 21 Aug 2022 03:56 |
| URI: | http://eprints.um.edu.my/id/eprint/33402 |
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