Toxoplasmosis: prevalence and risk factors

Nissapatorn, V. and Noor Azmi, M.A. and Cho, S.M. and Fong, M.Y. and Init, I. and Rohela, M. and Khairul Anuar, A. and Quek, K.F. and Latt, H.M. (2003) Toxoplasmosis: prevalence and risk factors. Journal of Obstetrics & Gynecology, 23 (6). pp. 618-624. ISSN 0144-3615

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The gene encoding the excretory-secretory antigen TES-120 of dog ascarid worm Toxocara canis was cloned into the bacterium Escherichia coli. The specificity of the recombinant TES- 120 antigen produced by the bacterium was investigated.A total of 45 human serum samples from patients infected with different helminthes and protozoa, including 8 cases of toxocariasis, were tested against the recombinant antigens in immunoblot assays. The results from the assays revealed that the recombinant TES-120 antigen reacted with sera from toxocariasis patients only. This highly specific recombinant TES-120 antigen can potentially be used for the development of an inexpensive serodiagnostic assay for human toxocariasis.

Item Type: Article
Additional Information: Department of Parasitology, Faculty of Medicine Building, University of Malaya, 50603 Kuala Lumpur, MALAYSIA
Uncontrolled Keywords: Parasitology
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Fong Mun Yik
Date Deposited: 13 Jun 2012 01:39
Last Modified: 13 Jun 2012 01:39

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