Prospects of implant with locking plate in fixation of subtrochanteric fracture: experimental demonstration of its potential benefits on synthetic femur model with supportive hierarchical nonlinear hyperelastic finite element analysis

Latifi, H. and Rukmanikanthan, S. and Mansor, A. and Kamarul, Tunku and Bilgen, M. (2012) Prospects of implant with locking plate in fixation of subtrochanteric fracture: experimental demonstration of its potential benefits on synthetic femur model with supportive hierarchical nonlinear hyperelastic finite element analysis. BioMedical Engineering OnLine, 11 (1). p. 23. ISSN 1475-925X

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Abstract

Background: Effective fixation of fracture requires careful selection of a suitable implant to provide stability and durability. Implant with a feature of locking plate (LP) has been used widely for treating distal fractures in femur because of its favourable clinical outcome, but its potential in fixing proximal fractures in the subtrochancteric region has yet to be explored. Therefore, this comparative study was undertaken to demonstrate the merits of the LP implant in treating the subtrochancteric fracture by comparing its performance limits against those obtained with the more traditional implants; angle blade plate (ABP) and dynamic condylar screw plate (DCSP). Materials and Methods: Nine standard composite femurs were acquired, divided into three groups and fixed with LP (n = 3), ABP (n = 3) and DCSP (n = 3). The fracture was modeled by a 20mm gap created at the subtrochanteric region to experimentally study the biomechanical response of each implant under both axial static and dynamic loading paradigms. To confirm the experimental findings and to understand the critical interactions at the boundaries, the synthetic femur/implant systems were numerically analyzed by constructing hierarchical finite element models with nonlinear hyperelastic properties. The predictions from the analyses were then compared against the experimental measurements to demonstrate the validity of the numeric model, and to characterize the internal load distribution in the femur and load bearing properties of each implant. Results:The average measurements indicated that the constructs with ABP, DCPS and LP respectively had overall stiffness values of 70.9, 110.2 and 131.4N/mm, and exhibited reversible deformations of 12.4, 4.9 and 4.1mm when the applied dynamic load was 400N and plastic deformations of 11.3, 2.4 and 1.4mm when the load was 1000N. The corresponding peak cyclic loads to failure were 1100, 1167 and 1600N. The errors between the displacements measured experimentally or predicted by the nonlinear hierarchical hyperelastic model were less than 18. In the implanted femur heads, the principal stresses were spatially heterogeneous for ABP and DCSP but more homogenous for LP, meaning LP had lower stress concentrations. Conclusion: When fixed with the LP implant, the synthetic femur model of the subtrochancteric fracture consistently exceeds in the key biomechanical measures of stability and durability. These capabilities suggest increased resistance to fatigue and failure, which are highly desirable features expected of functional implants and hence make the LP implant potentially a viable alternative to the conventional ABP or DCSP in the treatment of the subtrochancteric femurfractures for the betterment of the clinical outcome.

Item Type: Article
Additional Information: Department of Orthopedic Surgery, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia Health and Translational Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
Uncontrolled Keywords: Locking plate, Angle blade plate, Dynamic condylar screw plate, Subtrochanteric fracture, Biomechanics, Finite element analysis, Hierarchical finite element modelling
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms Haslinda Lahuddin
Date Deposited: 04 Jun 2012 02:33
Last Modified: 10 Oct 2018 08:57
URI: http://eprints.um.edu.my/id/eprint/3197

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