Managing complications of radiation therapy in head and neck cancer patients: part IV. management of osteoradionecrosis

Ramli, R. and Ngeow, Wei Cheong and Rahman, R.A. and Chai, Wen Lin (2006) Managing complications of radiation therapy in head and neck cancer patients: part IV. management of osteoradionecrosis. Singapore Dental Journal, 28 (1). pp. 11-15. ISSN 0377-5291,

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Abstract

Head and neck cancer is becoming a more recognizable pathology to the general population and dentists. The modes of treatment include surgery and/or radiation therapy. Pretreatment dental assessment should be provided for these patients before they undergo radiation therapy. There are occasions, however, whereby head and neck cancer patients are not prepared optimally and, as a result, they succumb to complicated oral adverse effects after radiation therapy. Osteoradionecrosis (ORN) is a severe debilitating condition that impairs healing due to reduction in vascularity and osteocyte population in the affected bone. This article reviews methods of treatment used to treat ORN such as antibiotics, hyperbaric oxygen therapy, therapeutic ultrasound, surgery, and other modalities.

Item Type: Article
Funders: UNSPECIFIED
Additional Information: Cited By (since 1996): 1 Export Date: 5 April 2012 Source: Scopus PubMed ID: 17378336 Language of Original Document: English Correspondence Address: Ngeow, W.C.; Faculty of Dentistry, University of Malaya, 50603 Kuala Lumpur, Malaysia; email: ngeowy@um.edu.my References: Regaud, C., Sur la necrose des os attients par un processus cancereux et traiters par les radiations (1922) Compt Rend Soc de Biol, 87, p. 629; Morrish, R.B., Osteoradionecrosis in patients irradiated for head and neck carcinoma (1981) Cancer, 47, pp. 1980-1983; Marx, R.E., A new concept in the treatment of osteoradionecrosis (1983) J Oral Maxillofac Surg, 41, pp. 351-357; Hutchinson, I.L., Complications of radiotherapy in the head and neck: An orofacial surgeon's view (1996) Current Radiation Oncology, pp. 144-177. , Tobias JS, Thomas PRM, eds, London: Arnold; Vudiniabola, S., Pirone, C., Williamson, Goss, A.N., Hyperbaric oxygen in the prevention of osteoradionecrosis of the jaws (1999) Aust Dent J, 44, pp. 243-247; Joyston-Bechal, S., Management of oral complications following radiotherapy (1992) Dent Update, 19, pp. 232-238; Marx, R.E., Osteoradionecrosis: A new concept of its pathophysiology (1983) J Oral Maxillofac Surg, 41, pp. 283-288; Kanatas, A.N., Rogers, S.N., Martin, M.V., A practical guide for patients undergoing exodontia following radiotherapy to the oral cavity (2002) Dent Update, 29, pp. 498-503; Rothwell, B.R., Prevention and treatment of orofacial complications of radiotherapy (1987) J Am Dent Assoc, 114, pp. 316-332; Devlin, H., Barker, G.R., Prosthetic and surgical care of the elderly radiotherapy patient: The GDP's role (1988) Dent Update, 15, pp. 168-169; Carl, W., Ikner, C., Dental extractions after radiation therapy in the head and neck area and hard tissue replacement (HTR) therapy: A preliminary study (1998) J Prosthet Dent, 79, pp. 317-322; Haber-Cohen, A., Debuski, S., Management of oral and maxillofacial surgery procedures in irradiated patients (1990) Dent Clin North Am, 34, pp. 71-77; Kanatas, A.N., Rogers, S.N., Martin, M.V., A survey of antibiotic prescribing by maxillofacial consultants for dental extractions following radiotherapy to the oral cavity (2002) Br Dent J, 192, pp. 157-160; Marx, R.E., Johnson, R.P., Kline, S.N., Prevention of osteoradionecrosis: A randomised prospective clinical trial of hyper-baric oxygen versus penicillin (1985) J Am Dent Assoc, 111, pp. 49-54; Mealey, B.L., Semba, S.E., Hallmon, W.W., The head and neck radiotherapy patient: Part 2. 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Uncontrolled Keywords: Head and neck cancer Hyperbaric oxygen Osteoradionecrosis Radiation therapy Ultrasound therapy bone necrosis head and neck tumor human jaw disease review risk factor Head and Neck Neoplasms Humans Hyperbaric Oxygenation Jaw Diseases Risk Factors Ultrasonic Therapy
Subjects: R Medicine > RK Dentistry
Divisions: Faculty of Dentistry > Dept of General Dental Practice And Oral & Maxillofacial Imaging
Depositing User: Associate Professor Dr. Wen Lin Chai
Date Deposited: 03 May 2012 02:21
Last Modified: 27 Sep 2019 08:44
URI: http://eprints.um.edu.my/id/eprint/3086

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