Breast cancer in a multi-ethnic Asian setting: results from the Singapore-Malaysia hospital-based breast cancer registry

Pathy, Nirmala Bhoo and Yip, Cheng Har and Mohd Taib, Nur Aishah and Hartman, Mikael and Saxena, Nakul and Iau, Philip and Bulgiba, Awang and Lee, Soo Chin and Lim, S.E. and Wong, John E.L. and Verkooijen, Helena M. (2011) Breast cancer in a multi-ethnic Asian setting: results from the Singapore-Malaysia hospital-based breast cancer registry. The Breast, 20 (Spp.2). S75-S80. ISSN 0960-9776, DOI https://doi.org/10.1016/j.breast.2011.01.015.

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Official URL: https://doi.org/10.1016/j.breast.2011.01.015

Abstract

Two hospital-based breast cancer databases (University Malaya Medical Center, Malaysia n = 1513 and National University Hospital, Singapore n = 2545) were merged into a regional registry of breast cancer patients diagnosed between 1990 and 2007. A review of the data found 51% of patients diagnosed before the age of 50 years. and 72% percent of the women were Chinese followed by Malays (16%), Indians (8%), and other races (4%). Median tumor size at presentation was 26 mm and about 25% of patients presented with TNM stage III or IV disease. Most tumors were of ductal histology (87%). Fifty-seven percent of tumors were estrogen receptor positive and 40% were poorly differentiated. Of those patients who had surgery, 70% had mastectomy while 30% had breast conserving surgery. Overall, chemotherapy was administered to 56% of patients and hormonal treatment to 60%. Five-year overall survival was 82.5% in patients with TNM stage 0 to stage II cancer, and 30.2% in those with later stages. (C) 2011 Elsevier Ltd. All rights reserved.

Item Type: Article
Funders: UNSPECIFIED
Additional Information: Pathy, Nirmala Bhoo Yip, Cheng Har Taib, Nur Aishah Hartman, Mikael Saxena, Nakul Lau, Philip Bulgiba, Awang M. Lee, Soo Chin Lim, Siew Eng Wong, John E. L. Verkooijen, Helena M. 2
Uncontrolled Keywords: Breast Cancer; Asian; Asia; Cancer registry
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Awang Bulgiba Awang Mahmud
Date Deposited: 09 May 2012 03:49
Last Modified: 15 Nov 2019 08:31
URI: http://eprints.um.edu.my/id/eprint/3058

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