Breast cancer in a multi-ethnic Asian setting: results from the Singapore-Malaysia hospital-based breast cancer registry

Pathy, N.B. and Yip, C.H. and Taib, N.A. and Hartman, M. and Saxena, N. and Lau, P. and Bulgiba, A.M. and Lee, S.C. and Lim, S.E. and Wong, J.E.L. and Verkooijen, H.M. (2011) Breast cancer in a multi-ethnic Asian setting: results from the Singapore-Malaysia hospital-based breast cancer registry. Breast, 20 (2). S75-S80. ISSN 0960-9776

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Abstract

Two hospital-based breast cancer databases (University Malaya Medical Center, Malaysia n = 1513 and National University Hospital, Singapore n = 2545) were merged into a regional registry of breast cancer patients diagnosed between 1990 and 2007. A review of the data found 51% of patients diagnosed before the age of 50 years. and 72% percent of the women were Chinese followed by Malays (16%), Indians (8%), and other races (4%). Median tumor size at presentation was 26 mm and about 25% of patients presented with TNM stage III or IV disease. Most tumors were of ductal histology (87%). Fifty-seven percent of tumors were estrogen receptor positive and 40% were poorly differentiated. Of those patients who had surgery, 70% had mastectomy while 30% had breast conserving surgery. Overall, chemotherapy was administered to 56% of patients and hormonal treatment to 60%. Five-year overall survival was 82.5% in patients with TNM stage 0 to stage II cancer, and 30.2% in those with later stages. (C) 2011 Elsevier Ltd. All rights reserved.

Item Type: Article
Additional Information: Pathy, Nirmala Bhoo Yip, Cheng Har Taib, Nur Aishah Hartman, Mikael Saxena, Nakul Lau, Philip Bulgiba, Awang M. Lee, Soo Chin Lim, Siew Eng Wong, John E. L. Verkooijen, Helena M. 2
Uncontrolled Keywords: Breast Cancer, Asian, Asia, Cancer registry
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Awang Bulgiba Awang Mahmud
Date Deposited: 09 May 2012 03:49
Last Modified: 11 Dec 2014 08:38
URI: http://eprints.um.edu.my/id/eprint/3058

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