Successful treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) in Systemic Lupus Erythematosus (SLE) with oral cyclophosphamide

Jasmin, R.; Sockalingam, S.; Shahrizaila, N.; Cheah, T.E.; Zain, A.; Goh, K.J. (2012) Successful treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) in Systemic Lupus Erythematosus (SLE) with oral cyclophosphamide. Lupus. ISSN 0961-2033

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Abstract

Peripheral neuropathy is a known manifestation of systemic lupus erythematosus. However, the association of primary autoimmune inflammatory neuropathies such as chronic inflammatory demyelinating polyneuropathy (CIDP) with SLE is uncommon. We report a 26-year-old man who simultaneously presented with severe CIDP and photosensitive rash, but was unresponsive to intravenous immunoglobulin infusion and continued to progress. He was found to have underlying SLE and improved with combined corticosteroid and immunosuppressive therapy with oral cyclophosphamide. CIDP with underlying SLE may be more resistant to conventional therapy with IVIG, requiring the addition of other immunosuppressive agents.

Item Type: Article
Journal or Publication Title: Lupus
Additional Information: Department of Medicine, University of Malaya, Malaysia
Uncontrolled Keywords: Peripheral Neuropathy
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Mr. Faizal Hamzah
Date Deposited: 26 Mar 2012 09:20
Last Modified: 11 Dec 2013 15:15
URI: http://eprints.um.edu.my/id/eprint/2973

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