Evaluation of antioxidant activity and phytochemical composition of Baeckea frutescens and Leptospermum javanicum essential oils

Saad, Hazwani Mat and Rahman, Syarifah Nur Syed Abdul and Navanesan, Suerialoasan and Tan, Chun Hoe and Manickam, Sugumaran and Abd Malek, Sri Nurestri and Sim, Kae Shin (2021) Evaluation of antioxidant activity and phytochemical composition of Baeckea frutescens and Leptospermum javanicum essential oils. South African Journal of Botany, 141. pp. 474-479. ISSN 0254-6299, DOI https://doi.org/10.1016/j.sajb.2021.06.005.

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Abstract

Plant extracts such as essential oils are a common yet valuable source of antioxidants for application in pharmaceutical and food preservative. In this study, the phytochemical profile of Baeckea frutescens (BF) and Leptospermum javanicum (LJ) essential oils were determined using GC-FID and GC/MS analyses. This resulted in the identification of 13 components (82.03%) in the essential oil of BF, the major compounds were p-cymene (1, 31.06%), alpha-pinene (2, 24.53%), 1,8-cineole (3, 11.49%), and gamma-terpinene (4, 8.31%). Whilst, 32 components (84.62%) were detected in the essential oil of LJ, in which sabinene (5, 25.83%) and alpha-pinene (2, 12.17%) were the major components. The antioxidant activity of the essential oils were evaluated using a wide array of radical scavenging assays, such as DPPH radical scavenging, reducing power, metal chelating, and beta-carotene bleaching assays. From the results, both BF and LJ essential oils exhibited appreciable antioxidant activity in all assays (EC50 0.29-1.39 mg/mL), except in DPPH radical scavenging assay (EC50 > 50 mg/mL). The essential oil of BF had a higher overall antioxidant capacity than LJ. With reference to the phytochemical profile, compounds 1-5 are potent antioxidants, which may substantially contribute to the antioxidant capacity of the essential oils. (C) 2021 SAAB. Published by Elsevier B.V. All rights reserved.

Item Type: Article
Funders: University of Malaya Postgraduate Research Grant (PPP) (PG080-2013B), University of Malaya Research Grant (UMRG) (RG082-13BIO), Fundamental Research Grant Scheme (FRGS) (FP006-2013A)
Uncontrolled Keywords: Chemotype; GC/MS; Myrtaceae; Oxidative stress; Radical scavenging activity
Subjects: Q Science > QK Botany
Divisions: Faculty of Science
Depositing User: Ms Zaharah Ramly
Date Deposited: 06 Apr 2022 03:51
Last Modified: 06 Apr 2022 03:51
URI: http://eprints.um.edu.my/id/eprint/28693

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