Kapoor, Bhupinder and Gulati, Monica and Gupta, Reena and Singh, Sachin Kumar and Gupta, Mukta and Nabi, Arshid and Chawla, Pooja A. (2021) A review on plant flavonoids as potential anticancer agents. Current Organic Chemistry, 25 (6). pp. 737-747. ISSN 1385-2728, DOI https://doi.org/10.2174/1385272824999201126214150.
Full text not available from this repository.Abstract
Flavonoids are polyphenolic compounds that are mainly derived from fruits and vegetables and constitute an essential part of plant-derived beverages such as green tea, wine and cocoa-based products. They have been shown to possess anticancer effects via different mechanisms such as carcinogen inactivation, antiproliferation, cell cycle arrest, induction of apoptosis and differentiation, inhibition of angiogenesis, anti-oxidation and reversal of multidrug resistance or a combination of any two or more of these mechanisms. The present review summarizes the chemistry, biosynthesis and anticancer evaluation of flavonoids in both animal and human studies. A special emphasis has been placed on the flavonoids that are being screened in different phases of clinical trials for chemopmtective action against various cancers.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Flavonoids; anticancer; Chemoprotection; Clinical trials; Apoptosis; Antiproliferation |
| Subjects: | Q Science > Q Science (General) Q Science > QD Chemistry |
| Divisions: | Faculty of Science > Department of Chemistry |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 16 Aug 2022 07:57 |
| Last Modified: | 16 Aug 2022 07:57 |
| URI: | http://eprints.um.edu.my/id/eprint/28645 |
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