Yoon, Jung-Pil and Nam, Jae-Sik and Zainal Abidin, Mohd Fitry and Kim, Seon-Ok and Lee, Eun-Ho and Choi, In-Cheol and Chin, Ji-Hyun (2021) Comparison of preoperative nutritional indexes for outcomes after primary esophageal surgery for esophageal squamous cell carcinoma. Nutrients, 13 (11). ISSN 2072-6643, DOI https://doi.org/10.3390/nu13114086.
Full text not available from this repository.Abstract
Background: This study aimed to compare the controlling nutritional status (CONUT) score, prognostic nutritional index (PNI), and geriatric nutritional risk index (GNRI) for predicting postoperative outcomes in patients with esophageal squamous cell carcinoma undergoing esophagectomy. Methods: We retrospectively reviewed the data of 1265 consecutive patients who underwent elective esophageal surgery. The patients were classified into no risk, low-risk, moderate-risk, and high-risk groups based on nutritional scores. Results: The moderate-risk (hazard ratio HR]: 1.55, 95% confidence interval CI]: 1.24-1.92, p < 0.001 in CONUT; HR: 1.61, 95% CI: 1.22-2.12, p = 0.001 in GNRI; HR: 1.65, 95% CI: 1.20-2.26, p = 0.002 in PNI) and high-risk groups (HR: 1.91, 95% CI: 1.47-2.48, p < 0.001 in CONUT; HR: 2.54, 95% CI: 1.64-3.93, p < 0.001 in GNRI; HR: 2.32, 95% CI: 1.77-3.06, p < 0.001 in PNI) exhibited significantly worse 5-year overall survival (OS) compared with the no-risk group. As the nutritional status worsened, the trend in the OS rates decreased (p for trend in all indexes < 0.05). Conclusions: Malnutrition, evaluated by any of three nutritional indexes, was an independent prognostic factor for postoperative survival.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Esophageal cancer; Controlling nutritional status score; Prognostic nutritional index; Geriatric nutritional risk index; Survival |
| Subjects: | Q Science > QP Physiology |
| Divisions: | Faculty of Medicine |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 14 Mar 2022 03:09 |
| Last Modified: | 14 Mar 2022 03:09 |
| URI: | http://eprints.um.edu.my/id/eprint/28568 |
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