The global distribution of permanent canine hypodontia: A systematic review

Sivarajan, Saritha and Mani, Shani Ann and John, Jacob and Fayed, Mona M. Salah and Kook, Yoon-Ah and Wey, Mang Chek (2021) The global distribution of permanent canine hypodontia: A systematic review. Korean Journal of Orthodontics, 51 (1). pp. 55-74. ISSN 2234-7518, DOI https://doi.org/10.4041/kjod.2021.51.1.55.

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Abstract

Objective: To systematically review studies on canine agenesis prevalence in different populations and continents, based on the jaw, sex, location, and associated dental anomalies. Methods: Electronic and hand searches of English literature in PubMed, Web of Science, Scopus, OpenGrey, and Science Direct were conducted, and the authors were contacted when necessary. Observational studies (population-based, hospital/clinic-based, and cross-sectional) were included. For study appraisal and synthesis, duplicate selection was performed independently by two reviewers. Study quality was assessed using a modified Strengthening the Reporting of Observational Studies in Epidemiology checklist, with main outcome of prevalence of canine agenesis. Results: The global population prevalence of canine agenesis was 0.30% (0.0-4.7%), highest in Asia (0.54%), followed by Africa (0.33%), and the least in Europe and South America (0.19% in both continents). Canine agenesis was more common in the maxilla (88.57%), followed by both maxilla and mandible (8.57%), and the least common was mandible- only presentation (2.86%). The condition was more common in females (female:male ratio = 1.23), except in Asia (female:male ratio = 0.88) and Africa (female:male ratio = 1). In Asia, unilateral agenesis was almost twice as prevalent as bilateral, but in Europe, the bilateral form was more common. Conclusions: The overall prevalence of canine agenesis is 0.30%, with the highest prevalence in Asia, followed by Africa, Europe, and South America. The condition is more common in the maxilla than the mandible, and in females than males (except in Asia and Africa), with unilateral agenesis being more common in Asia and the bilateral form showing a greater prevalence in Europe.

Item Type: Article
Funders: UNSPECIFIED
Uncontrolled Keywords: Canine agenesis; Prevalence; Continents
Subjects: R Medicine > RK Dentistry
Divisions: Faculty of Dentistry > Dept of Children’s Dentistry And Orthodontics
Depositing User: Ms Zaharah Ramly
Date Deposited: 15 Aug 2022 06:26
Last Modified: 15 Aug 2022 06:26
URI: http://eprints.um.edu.my/id/eprint/28547

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