Tan, Guo Jeng and Tan, Maw Pin and Luben, Robert N. and Wareham, Nicholas J. and Khaw, Kay-Tee and Myint, Phyo Kyaw (2021) The relationship between alcohol intake and falls hospitalization: Results from the EPIC-Norfolk. Geriatrics & Gerontology International, 21 (8). pp. 657-663. ISSN 1444-1586, DOI https://doi.org/10.1111/ggi.14219.
Full text not available from this repository.Abstract
Aim To evaluate the relationship between habitual alcohol consumption and the risk of falls hospitalization. Methods The EPIC-Norfolk is a prospective population-based cohort study in Norfolk, UK. In total, 25 637 community dwelling adults aged 40-79 years were recruited. Units of alcohol consumed per week were measured using a validated Food Frequency Questionnaire. The main outcome was the first hospital admission following a fall. Results Over a median follow-up period of 11.5 years (299 211 total person years), the cumulative incidence function (95% confidence interval) of hospitalized falls at 121-180 months for non-users, light (>0 to <= 7 units/week), moderate (>7 to <= 28 units/week) and heavy (>28 units/week) were 11.08 (9.94-12.35), 7.53 (7.02-8.08), 5.91 (5.29-6.59) and 8.20 (6.35-10.56), respectively. Moderate alcohol consumption was independently associated with a reduced risk of falls hospitalization after adjustment for most major confounders (hazard ratio = 0.88; 95% confidence interval 0.79-0.99). The relationship between light alcohol consumption and falls hospitalization was attenuated by gender differences. Alcohol intake higher than the recommended threshold of 28 units/week was associated with an increased risk of falls hospitalization (hazard ratio 1.40 1.14-1.73]). Conclusions Moderate alcohol consumption appears to be associated with a reduced risk of falls hospitalization, and intake above the recommended limit is associated with an increased risk. This provides incentive to limit alcohol consumption within the recommended range and has important implications for public health policies for aging populations. Geriatr Gerontol Int 2021; center dot center dot: center dot center dot-center dot center dot.
| Item Type: | Article |
|---|---|
| Funders: | UK Research & Innovation (UKRI) Medical Research Council UK (MRC) European Commission (MC-UU_12015/1), UK Research & Innovation (UKRI) Medical Research Council UK (MRC) European Commission (MC-UU_12015/1), Cancer Research UK (C864/A14136) |
| Uncontrolled Keywords: | Alcohol; Elderly; Falls; Geriatric; Hospitalization |
| Subjects: | R Medicine |
| Divisions: | Faculty of Medicine |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 15 Aug 2022 04:36 |
| Last Modified: | 15 Aug 2022 04:36 |
| URI: | http://eprints.um.edu.my/id/eprint/28500 |
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