Shear wave elastography: A review on the confounding factors and their potential mitigation in detecting chronic kidney disease

Lim, William T. H. and Ooi, Ean H. and Foo, Ji J. and Ng, Kwan Hoong and Wong, Jeannie Hsiu Ding and Leong, Sook S. (2021) Shear wave elastography: A review on the confounding factors and their potential mitigation in detecting chronic kidney disease. Ultrasound in Medicine and Biology, 47 (8). pp. 2033-2047. ISSN 0301-5629, DOI https://doi.org/10.1016/j.ultrasmedbio.2021.03.030.

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Abstract

Early detection of chronic kidney disease is important to prevent progression of irreversible kidney damage, reducing the need for renal transplantation. Shear wave elastography is ideal as a quantitative imaging modality to detect chronic kidney disease because of its non-invasive nature, low cost and portability, making it highly accessible. However, the complexity of the kidney architecture and its tissue properties give rise to various confounding factors that affect the reliability of shear wave elastography in detecting chronic kidney disease, thus limiting its application to clinical trials. The objective of this review is to highlight the confounding factors presented by the complex properties of the kidney, in addition to outlining potential mitigation strategies, along with the prospect of increasing the versatility and reliability of shear wave elastography in detecting chronic kidney disease. (C) 2021 World Federation for Ultrasound in Medicine & Biology. All rights reserved.

Item Type: Article
Funders: UNSPECIFIED
Uncontrolled Keywords: Shear wave elastography; Chronic kidney disease; Ultrasound; Medical imaging; Viscoelasticity; Anisotropy; Hemodynamics; Fibrosis; Acoustic radiation force; Stiffness
Subjects: R Medicine > R Medicine (General)
Divisions: Faculty of Medicine
Faculty of Medicine > Biomedical Imaging Department
Depositing User: Ms Zaharah Ramly
Date Deposited: 15 Aug 2022 01:50
Last Modified: 15 Aug 2022 01:50
URI: http://eprints.um.edu.my/id/eprint/28493

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