Smart stimuli-responsive nanocarriers for the cancer therapy - nanomedicine

Murugan, Baranya and Sagadevan, Suresh and Fatimah, Is and Oh, Won-Chun and Hossain, Mohd Abd Motalib and Johan, Mohd Rafie (2021) Smart stimuli-responsive nanocarriers for the cancer therapy - nanomedicine. Nanotechnology Reviews, 10 (1). pp. 933-953. ISSN 2191-9089, DOI https://doi.org/10.1515/ntrev-2021-0067.

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Abstract

Nanomedicine is ongoing current research in the applications of nanotechnology for cancer therapy. Simply from a technology perspective, this field of research has an enormous broadening and success to date. Recently, nanomedicine has also made inroads in the treatment of cancer. Stimuli-responsive nanoparticles are an emerging field of research because its targeting capacity is of great interest in the treatment of cancer. The responsive nano particles are efficient in encountering different internal biological stimuli (acidic, pH, redox, and enzyme) and external stimuli (temperature, ultrasounds, magnetic field, and light), which are used as smart nanocarriers for delivery of the chemotherapeutic and imaging agents for cancer therapy. In-depth, the responsive nanocarrier that responds to the biological cues is of pronounced interest due to its capability to provide a controlled release profile at the tumor-specific site. The outlook of this review focuses on the stimuli-responsive nanocarrier drug delivery systems in sequence to address the biological challenges that need to be evaluated to overcome conventional cancer therapy.

Item Type: Article
Funders: Universiti Malaya (RU001-2019), Universiti Malaya (RU001-2020), Universiti Malaya (RU001-2021)
Uncontrolled Keywords: Nanocarrier; Stimuli-responsive; Drug delivery; Gene therapy; Targeted therapy; Photodynamic therapy
Subjects: Q Science > QC Physics
Q Science > QD Chemistry
Divisions: Deputy Vice Chancellor (Research & Innovation) Office > Nanotechnology & Catalysis Research Centre
Depositing User: Ms Zaharah Ramly
Date Deposited: 12 Aug 2022 06:55
Last Modified: 12 Aug 2022 06:55
URI: http://eprints.um.edu.my/id/eprint/28482

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