Longitudinal assessment between lifestyle-related risk factors and a composite cardiovascular disease (CVD) risk index among adolescents in Malaysia

Thangiah, Nithiah and Su, Tin Tin and Chinna, Karuthan and Jalaludin, Muhammad Yazid and Mohamed, Mohd Nahar Azmi and Majid, Hazreen Abdul (2021) Longitudinal assessment between lifestyle-related risk factors and a composite cardiovascular disease (CVD) risk index among adolescents in Malaysia. Scientific Reports, 11 (1). ISSN 2045-2322, DOI https://doi.org/10.1038/s41598-021-98127-0.

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Abstract

The study aims to create a composite risk index of CVD among adolescents and examine the influence of demographic, socioeconomic and lifestyle-related risk factors on the composite risk index of biological CVD risk factors among adolescents in Malaysia. A Malaysian adolescent cohort of 1320 adolescents were assessed at 13, 15 and 17 years. Seven biological CVD risk factors with moderate correlation were identified, standardized and averaged to form a composite CVD risk index. Generalised estimating equation using longitudinal linear regression was used to examine the effects of changes in adolescent lifestyle-related risk factors on the composite CVD risk index over time. From the ages 13 to 17 years, physical fitness (beta = - 0.001, 90% CI = - 0.003, 0.00002) and BMI (beta = 0.051, 95% CI = 0.042, 0.060) were significant predictors of attaining high scores of CVD risk. Female (beta = 0.118, 95% CI = 0.040, 0.197), Chinese (beta = 0.122, 95% CI = 0.006, 0.239), Indians (beta = - 0.114, 95% CI = - 0.216, - 0.012) and adolescents from rural schools (beta = 0.066, 95% CI = - 0.005, 0.136) were also found to be considerably significant. A more robust and gender-specific intervention programme focusing on healthy lifestyle (including achieving ideal BMI and improving physical fitness) need to be implemented among school-going adolescents.

Item Type: Article
Funders: Universiti Malaya [UMRP022A-14HTM] [RMF002-2020] [PG156-2015B]
Uncontrolled Keywords: Physical-activity; Young-adults; Children; Health
Subjects: R Medicine > R Medicine (General)
R Medicine > RJ Pediatrics
R Medicine > RJ Pediatrics > Child health. Child health services
Divisions: Faculty of Medicine > Paediatrics Department
Depositing User: Ms Zaharah Ramly
Date Deposited: 02 Aug 2022 01:57
Last Modified: 02 Aug 2022 01:57
URI: http://eprints.um.edu.my/id/eprint/28378

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