Pulingam, Thiruchelvi and Thong, Kwai Lin and Appaturi, Jimmy Nelson and Lai, Chin Wei and Leo, Bey Fen (2021) Mechanistic actions and contributing factors affecting the antibacterial property and cytotoxicity of graphene oxide. Chemosphere, 281. ISSN 0045-6535, DOI https://doi.org/10.1016/j.chemosphere.2021.130739.
Full text not available from this repository.Abstract
Recent advances in the field of nanotechnology contributed to the increasing use of nanomaterials in the engineering, health and biological sectors. Graphene oxide (GO) has great potentials as it could be fine-tuned to be adapted into various applications, especially in the electrical, electronic, industrial and clinical fields. One of the important applications of GO is its use as an antibacterial material due to its promising activity against a broad range of bacteria. However, our understanding of the mechanism of action of GO towards bacteria is still lacking and is often less described. Therefore, a comprehensive overview of bactericidal mechanistic actions of GO and the roles of physicochemical factors including size, aggregation, functionalization and adsorption behavior contributing to its antibacterial activities are described in this review. As the use of GO is expected to increase exponentially in the health sector, the cytotoxicity of GO among the cell lines is also discussed. Thus, this review emphasizes the physicochemical characteristics of GO that can be tailored for optimal antibacterial properties that is of importance to the health industry.
| Item Type: | Article |
|---|---|
| Funders: | University of Malaya Impact Oriented Interdisciplinary Research Grants (IIRG003B-19FNW), University of Malaya Impact Oriented Interdisciplinary Research Grants (IIRG018A-2019), RU SATU grant (ST003-2020), Fundamental Research Grant Scheme (FP023-2020) |
| Uncontrolled Keywords: | Graphene oxide; Antibacterial activity; Mechanism of action; Physicochemical characteristics; Cytotoxicity |
| Subjects: | Q Science > Q Science (General) R Medicine > R Medicine (General) |
| Divisions: | Faculty of Medicine Deputy Vice Chancellor (Research & Innovation) Office > Nanotechnology & Catalysis Research Centre |
| Depositing User: | Ms Zaharah Ramly |
| Date Deposited: | 21 Jun 2022 04:50 |
| Last Modified: | 21 Jun 2022 04:50 |
| URI: | http://eprints.um.edu.my/id/eprint/27970 |
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