Efficient synthesis of some V-shaped methylene-bridged compounds via regioselective condensation

Zonouzi, Afsaneh and Hosseinzadeh, Fatemeh and Dehdari, Shahrzad and Abbasi, Alireza and Ng, Seik Weng (2021) Efficient synthesis of some V-shaped methylene-bridged compounds via regioselective condensation. Journal of the Chinese Chemical Society, 68 (7). pp. 1172-1176. ISSN 0009-4536, DOI https://doi.org/10.1002/jccs.202100033.

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Abstract

A number of new stable methanobenzo7,8]1,3] dioxocino4,5-d]pyrimidine-1,3(2H)-dione derivatives (4a-l) were synthesized using a simple one-pot procedure with considerable efficiency. Reaction parameters were further optimized in order to achieve a single-product procedure. Plausible routes for reaction progress were investigated and it was proved that the reaction goes through regioselective condensation yielding an interesting V-shaped structure. Spectral data of all products under study were used to elucidate the chemical structure and X-ray structure analysis was performed to unambiguously prove the proposed structure for 4c.

Item Type: Article
Funders: Research Council of the University of Tehran
Uncontrolled Keywords: Barbituric acid; Chromene; Methylene bridged; regioselective condensation; V-shaped molecules
Subjects: Q Science > QD Chemistry
Divisions: Faculty of Science
Depositing User: Ms Zaharah Ramly
Date Deposited: 07 Apr 2022 06:34
Last Modified: 07 Apr 2022 06:34
URI: http://eprints.um.edu.my/id/eprint/27888

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