Lee, Y.Y.; Bee, P.C.; Lee, C.K.; Naiker, M.; Ismail, R. (2011) Bullous pemphigoid in an elderly patient with myelodysplastic syndrome and refractory anemia coupled with excess of blast. Annals of Dermatology. ISSN 1013-9087Full text not available from this repository.
Bullous pemphigoid (BP) has a recognized association with solid organ tumors, but is relatively rare in hematological malignancies. We report a 67-year-old male who developed BP after being diagnosed with myelodysplastic syndrome and refractory anemia with excess of blast (RAEB). Skin biopsy elucidated sub-epidermal bulla using direct immunofluorescence, revealing linear C3 and IgG deposits along the basement membrane. His BP was recalcitrant to the conventional treatment and only responded to a combination of high dose oral prednisolone and azathioprine. The relative refractory nature of his condition and concurrent RAEB supports a paraneoplastic nature.
|Journal or Publication Title:||Annals of Dermatology|
|Additional Information:||Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia|
|Uncontrolled Keywords:||Bullous pemphigoid (BP)|
|Divisions:||Faculty of Medicine|
|Depositing User:||Mr. Faizal Hamzah|
|Date Deposited:||23 Feb 2012 10:48|
|Last Modified:||21 Dec 2014 16:04|
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