Prevalence of dark without pressure and angioid streaks in sickle cell disease

Lott, Pooi Wah and McKibbin, Martin (2021) Prevalence of dark without pressure and angioid streaks in sickle cell disease. Ophthalmic Surgery Lasers & Imaging Retina, 52 (11). pp. 620-622. ISSN 2325-8160, DOI https://doi.org/10.3928/23258160-20211026-01.

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Abstract

BACKGROUND AND OBJECTIVES: To investigate the prevalence of areas of dark without pressure (DWOP) and angioid streaks (AS) in patients with sickle cell disease (SCD). PATIENTS AND METHODS: This was a consecutive series of 77 adults with SCD. RESULTS: DWOP appeared as multiple patches in 35 of the affected eyes and as a single lesion in 3 eyes. OCT finding demonstrated the ellipsoid layer was hyporeflective in DWOP. AS were identified in six cases (3.9%) and were bilateral in five cases. The prevalence of AS was higher with increasing age, being 67% in the patients older than age 45 years. CONCLUSION: The prevalence of DWOP in adults with SCD is 25% in this study, which is higher than previously reported, and the prevalence of AS is around 4%, which is midway between prior estimates. Recognition of the clinical examination and imaging features of DWOP reduce the need for additional investigation.

Item Type: Article
Funders: UNSPECIFIED
Uncontrolled Keywords: Dark without pressure; Angioid streaks; Sickle cell disease
Subjects: R Medicine > RE Ophthalmology > Ophthalmology
Divisions: Faculty of Medicine > Department of Ophthalmology
Depositing User: Ms Zaharah Ramly
Date Deposited: 25 Apr 2022 06:46
Last Modified: 25 Apr 2022 06:46
URI: http://eprints.um.edu.my/id/eprint/26884

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