Salivary nicotine and cotinine concentrations in unstimulated and stimulated saliva

Robson, Noor Zurani and Bond, A.J. and Wolff, K. (2010) Salivary nicotine and cotinine concentrations in unstimulated and stimulated saliva. African Journal of Pharmacy and Pharmacology, 4 (2). 061-065. ISSN 1996-0816

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Abstract

Salivary nicotine and salivary cotinine is widely used in clinical and epidemiological studies to validate smoking cessation. However, the reported collection for salivary nicotine and salivary cotinine vary by technique and duration. This study investigated the influence of salivary collection by unstimulation and stimulation technique of the concentration of salivary nicotine and salivary cotinine. It was found that unstimulated technique produced the highest salivary nicotine concentration, whereas stimulated technique produced the highest salivary cotinine concentration. The results of this study suggest that it is important to standardise salivary nicotine and cotinine collection technique.

Item Type: Article
Additional Information: Cite as: Robson N, Bond AJ, Wolff K. Salivary nicotine and cotinine concentrations in unstimulated and stimulated saliva. African Journal of Pharmacy and Pharmacology. 2010 February;4(2):061-5.
Uncontrolled Keywords: Saliva, Smoker, Nicotine, Cotinine, Technique, Biological Marker, Oral, Verify, Passive, Tobacco, Smoke
Subjects: B Philosophy. Psychology. Religion > BF Psychology
H Social Sciences > H Social Sciences (General)
L Education > L Education (General)
R Medicine
Divisions: Faculty of Medicine
Depositing User: Noorzurani Robson
Date Deposited: 15 Feb 2012 07:31
Last Modified: 21 Dec 2014 08:09
URI: http://eprints.um.edu.my/id/eprint/2682

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