Primary Breast Angiosarcoma: Utilisation of Pre-surgical Magnetic Resonance Imaging (MRI) for Accurate Tumour Characterization and Planning – A Case Report and Literature Review

Ab Mumin, Nazimah and Rahmat, Kartini and Ramli Hamid, Marlina Tanty and Ng, Wei Lin and Chan, Wai Yee and Cheah, Xin Ying and See, Mee Hoong and Yip, Cheng Har (2021) Primary Breast Angiosarcoma: Utilisation of Pre-surgical Magnetic Resonance Imaging (MRI) for Accurate Tumour Characterization and Planning – A Case Report and Literature Review. Current Medical Imaging, 17 (4). pp. 552-558. ISSN 1573-4056

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Official URL: https://doi.org/10.2174/1573405616666201007161119

Abstract

Background: Primary breast angiosarcoma is a rare malignancy with non-specific clini-cal and radiological findings. Case Report: A 30-year-old lady presented with left breast pain and lumpiness for over one year. She has had several breast ultrasounds (US) and was treated for acute mastitis and abscess. Subse-quently, in view of the rapid growth of the lump and worsening pain, she was re-investigated with US, elastography, digital breast tomosynthesis (DBT) and MRI. MRI raised the suspicion of an-giosarcoma. The diagnosis was confirmed after biopsy and she underwent mastectomy. Discussion: Literature review on imaging findings of breast angiosarcoma, especially on MRI, is discussed. MRI features showed heterogeneous low signal intensity on T1 and high signal intensity on T2. Dynamic contrast enhancement (DCE) features included either early enhancement with or without washout in the delayed phase, and some reported central areas of non-enhancement. Conclusion: This case report emphasises on the importance of MRI in clinching the diagnosis of breast angiosarcoma, and hence, should be offered sooner to prevent diagnostic delay. © 2021 Bentham Science Publishers.

Item Type: Article
Uncontrolled Keywords: Breast angiosarcoma; Breast cancer; Digital breast tomosynthe-sis(DBT); Magnetic resonance imaging (MRI); Primary breast angiosarcoma; Ultrasound elastography
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 26 Jul 2021 02:49
Last Modified: 26 Jul 2021 02:49
URI: http://eprints.um.edu.my/id/eprint/25989

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