Xu, Jingwu and Ahmad, Ali and Jones, James F. and Dolcetti, Riccardo and Vaccher, Emanuela and Prasad, Umapati and Menezes, José (2000) Elevated Serum Transforming Growth Factor β1 Levels in Epstein-Barr Virus-Associated Diseases and Their Correlation with Virus-Specific Immunoglobulin A (IgA) and IgM. Journal of Virology, 74 (5). pp. 2443-2446. ISSN 0022-538X, DOI https://doi.org/10.1128/JVI.74.5.2443-2446.2000.
Full text not available from this repository.Abstract
Transforming growth factor β (TGF-β) is an immunosuppressive cytokine which can induce immunoglobulin A (IgA) switch and Epstein-Barr virus (EBV) replication in latently infected cells. Here we report elevated serum levels of TGF-β in various EBV-associated diseases correlating positively with EBV- specific IgA titers and negatively with IgM titers, suggesting a role for this cytokine in the pathogenesis of these diseases.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Antibodies, Viral; Epstein-Barr Virus Infections; Herpesvirus 4, Human; Humans; Immunoglobulin A; Immunoglobulin M; Regression Analysis; Transforming Growth Factor beta |
| Subjects: | R Medicine |
| Divisions: | Faculty of Medicine |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 12 Apr 2021 02:01 |
| Last Modified: | 12 Apr 2021 02:01 |
| URI: | http://eprints.um.edu.my/id/eprint/25856 |
Actions (login required)
 |
View Item |
