Combined prednisolone, azathioprine, and cyclophosphamide treatment for persistent proliferative glomerulonephritis in adults

Mukherjee, A.P. (1971) Combined prednisolone, azathioprine, and cyclophosphamide treatment for persistent proliferative glomerulonephritis in adults. The Lancet, 298 (7738). pp. 1350-1353. ISSN 0140-6736

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Official URL: https://doi.org/10.1016/S0140-6736(71)92365-8

Abstract

Twelve adults-seven with nephrotic syndrome due to proliferative glomerulonephritis and five with persistent proliferative glomerulonephritis-were given prednisolone alone, or in combination with azathioprine or with azathioprine and cyclophosphamide. Prednisolone alone or with azathioprine did not produce remission but on the combined prednisolone/azathioprine/cyclophosphamide treatment ten patients recovered completely. No serious toxic reactions to this regimen were ob served. Triple-drug therapy seems to interfere with the immune process more effectively than double therapy. © 1971.

Item Type: Article
Uncontrolled Keywords: Adolescent; Adult; Azathioprine; Chlorambucil; Cholesterol; Creatinine; Cyclophosphamide; Female; Glomerulonephritis; Human; Kidney Glomerulus; Male; Nephrotic Syndrome; Prednisolone; Prognosis; Proteinuria; Serum Albumin
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 30 Mar 2021 04:28
Last Modified: 30 Mar 2021 04:28
URI: http://eprints.um.edu.my/id/eprint/25809

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