An Overview of the Genetic Variations of the SARS-CoV-2 Genomes Isolated in Southeast Asian Countries

Yap, Polly Soo Xi and Tan, Tse Siang and Chan, Yoke Fun and Tee, Kok Keng and Kamarulzaman, Adeeba and Teh, Cindy Shuan Ju (2020) An Overview of the Genetic Variations of the SARS-CoV-2 Genomes Isolated in Southeast Asian Countries. Journal of Microbiology and Biotechnology, 30 (7). pp. 962-966. ISSN 1017-7825, DOI https://doi.org/10.4014/jmb.2006.06009.

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Official URL: https://doi.org/10.4014/jmb.2006.06009

Abstract

Monitoring the mutation dynamics of human severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critical in understanding its infectivity, virulence and pathogenicity for development of a vaccine. In an "age of mobility,"the pandemic highlights the importance and vulnerability of regionalization and labor market interdependence in Southeast Asia. We intend to characterize the genetic variability of viral populations within the region to provide preliminary information for regional surveillance in the future. By analyzing 142 complete genomes from South East Asian (SEA) countries, we identified three central variants distinguished by nucleotide and amino acid changes. Copyright © 2020 by The Korean Society for Microbiology and Biotechnology.

Item Type: Article
Funders: UNSPECIFIED
Uncontrolled Keywords: Coronavirus; COVID-19; Genetic variation; Mutation; SARS-CoV-2; Southeast Asia
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 26 Feb 2021 02:25
Last Modified: 26 Feb 2021 02:25
URI: http://eprints.um.edu.my/id/eprint/25769

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