Immunohistochemical features of extra-nodal NK/T cell lymphoma

Muhamad, H.M. and Ibrahim, N.I. and Zain, R.B. (2011) Immunohistochemical features of extra-nodal NK/T cell lymphoma. Oral Oncology, 47. S132-S132. ISSN 1368-8375

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Abstract

NK/T cell lymphoma is a destructive extranodal lymphoproliferative disorder of a putative natural killer (NK) cell lineage. This rare malignant lymphoma is difficult to diagnose due to the histological resemblance to reactive processes hence was once considered as an inflammatory lesion known as lethal midline granuloma or non-healing granuloma. Providentially, the advance in immunophenotyping has permit characterization of NK/T-cell lymphoma, as a distinct entity from other type of lymphoma. It is most commonly involved the nasal cavity, paranasal sinuses and hard palate and as the case we reported here of a NK/T-cell lymphoma in a 29 year old Indonesian man whom presented with an ulcer on the palate. The ulcer started on the pharynx and progressively involved the soft and hard palate. Eventually, the whole palate appeared necrosed with granulation tissue and the uvula was elongated and irregular.Immunohistochemical studies leads to the diagnosis of an extranodular NK/T cell lymphoma

Item Type: Article
Additional Information: ISI Document Delivery No.: 793IX Muhamad, H. M. Ibrahim, N. I. Zain, R. M. Z. 3rd World Congress of the International-Academy-of-Oral-Oncology Jul 14-17, 2011 Singapore, SINGAPORE Int Acad Oral Oncol Elsevier science bv Amsterdam 1
Uncontrolled Keywords: Oral squamous cell carcinoma, OSCC, lichenoid lesions, lichen planus, oral cancer, oral tumours, pemphigus, traumatic eosinophilic granuloma, aphthous ulcers, oral mucosal lesions, betel chewers mucosa, betel quid related lesions, betel quid, areca quid, tobacco quid, oral cancer screening, training and calibration, early detection, oral cancer awareness, biobanking, tissue bank, databank, oral cancer, tissue bank, research credibility, research ethics
Subjects: R Medicine > RK Dentistry > Oral surger
Divisions: Faculty of Dentistry > Dept of Oral Pathology & Oral Medicine & Periodontology
Depositing User: Prof. Dr. Rosnah Mohd Zain
Date Deposited: 09 Feb 2012 07:51
Last Modified: 11 Dec 2014 06:20
URI: http://eprints.um.edu.my/id/eprint/2575

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