Zhang, Xinrong and Goh, George B.B. and Chan, Wah Kheong and Wong, Grace L.H. and Fan, Jian Gao and Seto, Wai Kay and Huang, Yi Hsiang and Lin, Han Chieh and Lee, I‐Cheng and Lee, Hye Won and Kim, Seung Up and Chow, Wan Cheng and Wong, Vincent W.S. and Petta, Salvatore (2020) Unhealthy lifestyle habits and physical inactivity among Asian patients with non‐alcoholic fatty liver disease. Liver International, 40 (11). pp. 2719-2731. ISSN 1478-3223, DOI https://doi.org/10.1111/liv.14638.
Full text not available from this repository.Abstract
Background & Aims: Lifestyle modification is the cornerstone for the management of non-alcoholic fatty liver disease (NAFLD). We aim to understand lifestyle habits of NAFLD patients, compare across Asian regions and identify area of deficiency. Methods: In the multi-centre controlled attenuation parameter (CAP)-Asia study, we collected clinical data and lifestyle habit data of NAFLD patients from Singapore, mainland China, Hong Kong, Taiwan and Malaysia. Physical activity was assessed using the International Physical Activity Questionnaire. Results: A total of 555 patients were included in the final analysis (mean age 54.5 ± 11.2 years, 54.1% men and median liver stiffness 6.7 kPa). More patients from mainland China (27.4%) and Taipei (25.0%) were smokers. Modest drinking was more common in Taiwan (25.0%) and Hong Kong (18.2%); only 1.3% had binge drinking. Majority of patients drank coffee (64.0%) and tea (80.2%), with varying amounts and durations in different regions. Soft drinks consumption was most common in Singapore (62.2%) and Malaysia (57.7%). Only 29.7% of patients met the Physical Activity Guidelines Recommendations, with no major differences across regions. Patients with liver stiffness <10 kPa were more likely to report any vigorous activity, and sitting time was an independent factor associated with high CAP. Tea and coffee consumption were independently associated with high CAP and liver stiffness, respectively. Conclusions: Despite some heterogeneity, unhealthy lifestyle and physical inactivity are common across Asian regions. Patients with liver stiffness <10 kPa were more likely to report any vigorous activity. Healthcare providers may use the comparative data to identify areas of deficiency. © 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
| Item Type: | Article |
|---|---|
| Funders: | Gilead Sciences (IN‐US‐989‐5334) |
| Uncontrolled Keywords: | alcohol; coffee; liver fibrosis; non-alcoholic steatohepatitis; physical activity; tea |
| Subjects: | R Medicine |
| Divisions: | Faculty of Medicine |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 20 Jan 2021 06:27 |
| Last Modified: | 20 Jan 2021 06:27 |
| URI: | http://eprints.um.edu.my/id/eprint/25701 |
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