Chong, Heng Thay (2008) Multiple sclerosis in South East Asia and diagnostic criteria for Asians. Neurology Asia, 13 (2). pp. 145-146. ISSN 1823-6138,
Full text not available from this repository.Abstract
Multiple sclerosis is an uncommon disease in Southeast Asia, having been characterised only recently. The estimated prevalence is about 2 - 3/ 105, with high female to male ratio, but rare family history. As high as 40% of the patients had the optic-spinal phenotype; though patients in this region seldom progressed to the secondary progressive phase, disability was more severe due to severe spinal cord involvement. There is a great degree of overlap in clinical, radiological and laboratory features between the classical and the optic-spinal phenotypes, including long spinal cord involvement, few brain lesions, lower proportion of positive cerebrospinal fluid oligoclonal bands and anti-aquaporin-4 antibody. We proposed that future international diagnostic criteria need to take this into account.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | Myelooptic Neuropathy; Myelin Oligodendrocyte Glycoprotein; Aquaporin 4 |
| Subjects: | R Medicine |
| Divisions: | Faculty of Medicine |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 10 Dec 2020 02:39 |
| Last Modified: | 10 Dec 2020 02:39 |
| URI: | http://eprints.um.edu.my/id/eprint/25621 |
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