Singaporentine A: A New Indole Alkaloid from Kopsia singapurensis Ridl.

Awang, Khalijah and Ahmad, Kartini and Thomas, Noel Francis and Hirasawa, Yusuke and Takeya, Koichi and Mukhtar, Mat Ropi and Mohamad, Khalit and Morita, Hiroshi (2008) Singaporentine A: A New Indole Alkaloid from Kopsia singapurensis Ridl. Heterocycles, 75 (12). pp. 3051-3056. ISSN 0385-5414

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Official URL: https://doi.org/10.3987/COM-08-11438

Abstract

Study on chemical constituents from the leaves of Kopsia singapurensis (Apocynaceae) yielded a new indole alkaloid, singaporentine A (1) together with two known alkaloids, kopsifoline A (2) and kopsininic acid (3). The structure of 1 was elucidated by combination of various spectroscopic methods such as MS, UV, IR, ID and 2D NMR. Singaporentine A exhibited cytotoxic activity against P388 murine leukemia cells. © 2008 The Japan Institute of Heterocyclic Chemistry.

Item Type: Article
Uncontrolled Keywords: Melodinus; Tabernaemontana; Rauwolfia Alkaloid
Subjects: Q Science > QD Chemistry
R Medicine > RS Pharmacy and materia medica
Divisions: Faculty of Medicine
Faculty of Science > Dept of Chemistry
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 01 Sep 2020 08:38
Last Modified: 01 Sep 2020 08:38
URI: http://eprints.um.edu.my/id/eprint/25494

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