Potential use of plasma focus radiation sources in superficial cancer therapy

Poh, Hun Seng and Lee, Ming Chuan and Yap, Seong Shan and Teow, Sin Yeang and Bradley, D.A. and Yap, Seong Ling (2020) Potential use of plasma focus radiation sources in superficial cancer therapy. Japanese Journal of Applied Physics, 59 (SH). SHHB06. ISSN 0021-4922, DOI https://doi.org/10.35848/1347-4065/ab7c10.

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Official URL: https://doi.org/10.35848/1347-4065/ab7c10

Abstract

The new multidisciplinary field of plasma medicine combines plasma physics, electrical engineering, life sciences and clinical medicine. Bekeschus et al. [Plasma Processes Polym. 16, 1800033 (2019)]. Here we explore potential uses in medicine, most particularly cancer therapy, the plasma source being brought out of the field of industrial applications into the life sciences, the focus being on superficial cancer radiotherapy strategies. Existing radiotherapy practices for such cancers rely on the use of rather large facilities, most popularly the electron linear accelerator and X-ray tube-based devices. Conversely, a compact plasma radiation source can be housed in a relatively small space, there being considerable promise for such devices to produce the fluence requirements of radiotherapy for treatment of skin cancers. The present study of feasibility investigates the plasma focus device, with the emission produced by a single discharge shown to generate an X-ray dose of few tens of mGy. The X-ray dose is the integration of emission in the discharge durations of less than a μs, it is therefore possible using these devices to build up fractional irradiation dose through repetitive operation of the discharge system. © 2020 The Japan Society of Applied Physics.

Item Type: Article
Funders: UNSPECIFIED
Uncontrolled Keywords: Cancer radiotherapies; Clinical medicine; Discharge duration; Discharge systems; Electron linear accelerator; Plasma focus devices; Plasma radiation sources; Repetitive operations
Subjects: Q Science > Q Science (General)
Q Science > QC Physics
Divisions: Faculty of Science > Department of Physics
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 17 Aug 2020 06:45
Last Modified: 17 Aug 2020 06:45
URI: http://eprints.um.edu.my/id/eprint/25392

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