High throughput mutational profiling of signaling molecules in oral cancer

Zanaruddin, S.N.S. and Cheong, S.C. and Rahman, Z.A.A. and Abd Ghani, W.M.N.W. and Mustafa, W.M.W. and Zain, R.B. and Kong, Y.H. and Hor, S.Y. and Teo, S.H. (2011) High throughput mutational profiling of signaling molecules in oral cancer. Oral Oncology, 47. S115-S115. ISSN 1368-8375

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Abstract

It is well established that a plethora of mutations that occur in oncogenes and tumor-suppressor genes are the main drivers of tumorigenesis. The identification of these mutations provides important clues to the cellular processes of carcinogenesis and affords an opportunity for these genes to be used for diagnostic and therapeutic purposes. In comparison to cancers such as breast, lung and colorectal, there is a lack of systematic, large scale characterization of oncogenic mutations oralsquamous cell carcinoma (OSCC).

Item Type: Article
Additional Information: Zanaruddin, S. N. Syed Cheong, S. C. Rahman, Z. A. Abd Abd Ghani, W. M. N. Wan Mustafa, W. M. Wan Zain, R. Binti Kong, Yink Heay Hor, Seen Yii Teo, Soo-Hwang 3rd World Congress of the International-Academy-of-Oral-Oncology Jul 14-17, 2011 Singapore, SINGAPORE 1
Uncontrolled Keywords: Oral squamous cell carcinoma, OSCC, lichenoid lesions, lichen planus, oral cancer, oral tumours, pemphigus, traumatic eosinophilic granuloma, aphthous ulcers, oral mucosal lesions, betel chewers mucosa, betel quid related lesions, betel quid, areca quid, tobacco quid, oral cancer screening, training and calibration, early detection, oral cancer awareness, biobanking, tissue bank, databank, oral cancer, tissue bank, research credibility, research ethics.
Subjects: R Medicine > RK Dentistry > Oral surger
Divisions: Faculty of Dentistry > Dept of Oral Pathology & Oral Medicine & Periodontology
Depositing User: Prof. Dr. Rosnah Mohd Zain
Date Deposited: 11 Jan 2012 01:58
Last Modified: 25 Feb 2017 03:05
URI: http://eprints.um.edu.my/id/eprint/2483

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