The use of mycophenolate mofetil in treating patients with non responding aplastic anemia

Gan, Gin Gin and Leong, C.F. and Sangkar, J.V. and Teh, A. and Goh, K.Y. and Cheong, S.K. (2005) The use of mycophenolate mofetil in treating patients with non responding aplastic anemia. Medical Journal of Malaysia, 60 (3). pp. 311-313. ISSN 0300-5283,

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Abstract

Aplastic anemia is a relatively uncommon disease and conventional management options include immunosuppressive drugs and/or haematopoeitic stem cell transplantation. It is now known that the pathogenesis of aplastic anemia is immune mediated. Mycophenolate mofetil is a common immunosuppressive drug now used mainly in prophylaxis of graft rejection in organ transplant and also for prevention/treatment for graft versus host disease in haemtopoeitic stem cell transplantation. It is thought that mycophenolate mofetil may be useful in this group of patients. In this short report, mycophenolate mofetil was tried in 6 patients who had severe aplastic anemia with variable doses for a minimum duration of 9 months. The result has however not been encouraging.

Item Type:	Article
Funders:	UNSPECIFIED
Additional Information:	DH
Uncontrolled Keywords:	Aplastic anemia; immunosuppressive; mycophenolate mofetil
Subjects:	R Medicine
Divisions:	Faculty of Medicine
Depositing User:	Mr Jasny Razali
Date Deposited:	03 Jun 2020 06:58
Last Modified:	03 Jun 2020 06:58
URI:	http://eprints.um.edu.my/id/eprint/24590

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