Comparison of two monoclonal antibody kits with cell culture isolation in the detection of respiratory virus antigens

Khairullah, N.S. (1996) Comparison of two monoclonal antibody kits with cell culture isolation in the detection of respiratory virus antigens. Journal of the University of Malaya Medical Centre (JUMMEC), 1 (2). p. 58. ISSN 1823-7339,

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Official URL: https://jummec.um.edu.my/issue/view/661/Vol.1%2C%2...

Abstract

Two different preparations of monoclonal antibodies developed against respiratory viruses have been evaluated by the immunofluorescence antibody technique. The Chemicon monoclonal antibodies were found to be more efTicient at picking up positive specimens with a high sensitivity and specificity than Imagen monoclonal antibodies. However, the overall concordance rate of the monoclonal antibodies was 92.3%-100%. Generally, when compared with cell culture isolation, the immunofluorescence antibody technique was found to be more sensitive. The high quality of the Chemicon monoclonal antibodies contribute to their value in providing definitive diagnosis, within a few hours of specimen collection, thus allowing early management of patients, their contacts and control of hospital infection.

Item Type: Article
Funders: UNSPECIFIED
Uncontrolled Keywords: Comparison; monoclonal antibody kits; cell culture isolation; respiratory virus antigens
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Mr Jasny Razali
Date Deposited: 24 Mar 2021 01:43
Last Modified: 24 Mar 2021 01:43
URI: http://eprints.um.edu.my/id/eprint/24485

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