Dengue 2: (New guinea C strain) virus infection induces apoptosis

Shafee, Norazizah and AbuBakar, Sazaly (1997) Dengue 2: (New guinea C strain) virus infection induces apoptosis. Journal of the University of Malaya Medical Centre (JUMMEC), 2 (1). pp. 19-21. ISSN 1823-7339

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Official URL: https://jummec.um.edu.my/article/view/4399

Abstract

The ability of dengue 2 virus infection to induce apoptosis was investigated. Dengue 2 virus-infected African green monkey kidney cells {Vera}. showed the presence of about 2. 9'. 22 and 30 percent apoptotic cells on day 3. S. B. and 11 postinfection. respectively. Increased number of apoptotic cells corresponded with increasing number of dengue 2 antigen positive cells. Induction of internucleosomal DNA fragmentation. characteristic of apoptotic cells, was noted also in dengue 2 virus-infected mosquito cell (C6f36) cultures. These results suggested that dengue 2 virus infection in nitro stimulated apoptotic cellular responses.

Item Type: Article
Uncontrolled Keywords: Apoptosis; C6/36; dengue; Vero
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Mr Jasny Razali
Date Deposited: 01 Jun 2020 00:58
Last Modified: 01 Jun 2020 00:58
URI: http://eprints.um.edu.my/id/eprint/24377

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