Tappe, Dennis and Gross, Yvonne and Ngui, Romano and Rauch, Jessica and Tay, Sun Tee and Lim, Yvonne Ai Lian (2019) High Seroprevalence Against Typhus Group and Spotted Fever Group Rickettsiae in Rural Indigenous Populations of Peninsular Malaysia. Vector-Borne and Zoonotic Diseases, 19 (5). pp. 323-327. ISSN 1530-3667, DOI https://doi.org/10.1089/vbz.2018.2391.
Full text not available from this repository.Abstract
Rickettsioses of the typhus group (TG) and spotted fever group (SFG) are emerging bacterial infections worldwide, especially in the tropics. Only a few studies on these pathogens and their respective clinical diseases have been conducted in Malaysia. Here, we performed a seroprevalence study among 544 healthy, afebrile indigenous people (Orang Asli) from peninsular Malaysia for TG and SFG rickettsioses in nine rural and peri-urban settlements. The study population encompassed children, adolescents, and adults. The overall seroprevalence of rickettsiosis in the Orang Asli was 48.5%, with 27.9% seroprevalence against TG rickettsiae and 20.6% seroprevalence against SFG rickettsiae. In 7.9% of the study participants, antibodies against both rickettsial groups were found. The highest seropositivity rates against TG and SRG rickettsiae were detected in young children and adults. Overall, there were no gender differences. Seroprevalences were similar among inhabitants of different settlements, except for two localities. More studies are needed to shed more light on the ecology and risk factors for TG and SFG rickettsioses in Malaysia. © Copyright 2019, Mary Ann Liebert, Inc., publishers 2019.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | murine typhus; rickettsiosis; spotted fever |
| Subjects: | R Medicine |
| Divisions: | Faculty of Medicine |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 23 Dec 2019 03:04 |
| Last Modified: | 23 Dec 2019 03:04 |
| URI: | http://eprints.um.edu.my/id/eprint/23279 |
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