Cardiometabolic Risk Factors and Physical Activity Patterns Maximizing Fitness and Minimizing Fatness Variation in Malaysian Adolescents: A Novel Application of Reduced Rank Regression

Toumpakari, Zoi and Jago, Russell and Howe, Laura D. and Majid, Hazreen Abdul and Papadaki, Angeliki and Mohammadi, Shooka and Jalaludin, Muhammad Yazid and Dahlui, Maznah and Mohamed, Mohd Nahar Azmi and Tin, Tin Su and Johnson, Laura (2019) Cardiometabolic Risk Factors and Physical Activity Patterns Maximizing Fitness and Minimizing Fatness Variation in Malaysian Adolescents: A Novel Application of Reduced Rank Regression. International Journal of Environmental Research and Public Health, 16 (23). p. 4662. ISSN 1660-4601, DOI https://doi.org/10.3390/ijerph16234662.

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Official URL: https://doi.org/10.3390/ijerph16234662

Abstract

Patterns of physical activity (PA) that optimize both fitness and fatness may better predict cardiometabolic health. Reduced rank regression (RRR) was applied to identify combinations of the type (e.g., football vs. skipping), location and timing of activity, explaining variation in cardiorespiratory fitness (CRF) and Body Mass Index (BMI). Multivariable regressions estimated longitudinal associations of PA pattern scores with cardiometabolic health in n = 579 adolescents aged 13–17 years from the Malaysian Health and Adolescent Longitudinal Research Team study. PA pattern scores in boys were associated with higher fitness (r = 0.3) and lower fatness (r = −0.3); however, in girls, pattern scores were only associated with higher fitness (r = 0.4) (fatness, r = −0.1). Pattern scores changed by β = −0.01 (95% confidence interval (CI) −0.04, 0.03) and β = −0.08 (95% CI −0.1, −0.06) per year from 13 to 17 years in boys and girls respectively. Higher CRF and lower BMI were associated with better cardiometabolic health at 17 years, but PA pattern scores were not in either cross-sectional or longitudinal models. RRR identified sex-specific PA patterns associated with fitness and fatness but the total variation they explained was small. PA pattern scores changed little through adolescence, which may explain the limited evidence on health associations. Objective PA measurement may improve RRR for identifying optimal PA patterns for cardiometabolic health. © 2019 by the authors. Licensee MDPI, Basel, Switzerland.

Item Type: Article
Funders: Medical Research Council grant MR/P013821/1, University of Malaya Research Programme grant RP022-14HTM and IF017-2017, Career Development Award from the UK Medical Research Council [MR/M020894/1], University of Bristol, UK Medical Research Council (MC_UU_12013/6)
Uncontrolled Keywords: adolescents; body mass index; cardiometabolic health; cardiorespiratory fitness; physical activity; physical activity patterns; trajectory; reduced rank regression
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 16 Dec 2019 07:52
Last Modified: 16 Dec 2019 07:52
URI: http://eprints.um.edu.my/id/eprint/23227

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