Yap, Ning Yi and Yap, Foo Ngan and Perumal, Komathi and Rajandram, Retnagowri (2019) Circulating adiponectin as a biomarker in renal cell carcinoma: a systematic review and meta-analysis. Biomarkers, 24 (6). pp. 607-614. ISSN 1354-750X, DOI https://doi.org/10.1080/1354750X.2019.1634763.
Full text not available from this repository.Abstract
Context: Metabolic imbalance in renal cell carcinoma (RCC) can lead to abnormal adiponectin levels. Objective: To evaluate circulating adiponectin as a detection or predictive marker for RCC. Methods: A comprehensive literature search and meta-analysis was performed on studies reporting circulating adiponectin levels and RCC. The meta-analysis was performed using RevMan. Results: Seven studies compared the circulating adiponection levels between RCC cases and controls. Adiponectin level was significantly lower in RCC cases compared to controls at pre-diagnosis and pre-operative time-points. RCC stage, grade and subtype did not affect adiponectin levels. Conclusion: Low circulating adiponectin could be a predictive or risk factor for RCC. © 2019, © 2019 Informa UK Limited, trading as Taylor & Francis Group.
| Item Type: | Article |
|---|---|
| Funders: | University of Malaya Research Grant RG393/17AFR |
| Uncontrolled Keywords: | Adiponectin; adipokine; circulating; obesity; renal cell carcinoma |
| Subjects: | R Medicine |
| Divisions: | Faculty of Medicine |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 27 Nov 2019 07:23 |
| Last Modified: | 27 Nov 2019 07:23 |
| URI: | http://eprints.um.edu.my/id/eprint/23122 |
Actions (login required)
 |
View Item |
