Significant pulmonary disease burden in treatment resistant disseminated cryptococcal infection: A case report

Viswanathan Shanthakumar, Shanthi and Tai, Mei Ling Sharon and Rais Sanusi, Abdul and Sivalingam, Sivakumar and Zakai, Saad Bader (2017) Significant pulmonary disease burden in treatment resistant disseminated cryptococcal infection: A case report. Indian Journal of Thoracic and Cardiovascular Surgery, 33 (4). pp. 355-358. ISSN 0970-9134, DOI https://doi.org/10.1007/s12055-017-0545-7.

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Official URL: https://doi.org/10.1007/s12055-017-0545-7

Abstract

Cryptococcus neoformans causes severe disseminated infection in immunocompromised individuals. We report a case of an immunocompetent adult male who presented with treatment-resistant central nervous system manifestations and significant pulmonary disease burden. Hematology and lumbar puncture were positive, aided by computerized tomography-guided histological confirmation. Despite medical therapy, there was inadequate resolution, and surgical resection was performed. On follow-up, investigations showed complete resolution, and the patient has remained disease-free at 5 years. This highlights the importance of looking for other sites in resistant cryptococcal meningitis and the value of cardiothoracic intervention for slowly resolving pulmonary cryptococcomas.

Item Type: Article
Funders: UNSPECIFIED
Uncontrolled Keywords: Cryptococcal meningitis; Disseminated; Immunocompetent host
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 24 Oct 2019 06:27
Last Modified: 17 Dec 2019 01:59
URI: http://eprints.um.edu.my/id/eprint/22842

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