The antioxidant activities, cytotoxic properties, and identification of water-soluble compounds of Ficus deltoidea leaves

Abrahim, Noor Nazirahanie and Abdul-Rahman, Puteri Shafinaz and Aminudin, Norhaniza (2018) The antioxidant activities, cytotoxic properties, and identification of water-soluble compounds of Ficus deltoidea leaves. PeerJ, 6. e5694. ISSN 2167-8359

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Official URL: https://doi.org/10.7717/peerj.5694

Abstract

Leaves from three varieties of Ficus deltoidea, colloquially termed small-(FDS), medium-(FDM), and big-type leaf (FDB), were subjected to water extraction. The crude extracts were fractionated using water (WF) and ethyl acetate (EAF). The phenolic and flavonoid content, antioxidant activity, and cytotoxicity of the fractions were investigated. The EAF had the highest phenolic and flavonoid content compared to the other FDS fractions. Conversely, the FDM crude extract had the highest phenolic and flavonoid content compared to the otherFDMsamples. Antioxidant activity was highest in the FDB crude extract. Ultra-high-performance liquid chromatography showed that two compounds, vitexin and coumaric acid, were present in the FDB crude extract. Additionally, the F. deltoidea leaves caused no signs of toxicity in a normal liver cell line. Our findings show that F. deltoidea varieties have excellent antioxidant activity with no cytotoxic effects on normal liver cells.

Item Type: Article
Uncontrolled Keywords: Antioxidant; Ficus deltoidea; Flavonoids; Phenolic acid
Subjects: Q Science > Q Science (General)
Q Science > QH Natural history
R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 14 Oct 2019 02:24
Last Modified: 14 Oct 2019 02:24
URI: http://eprints.um.edu.my/id/eprint/22722

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