Anuar, Nadzirah Sofia and Basirun, Wan Jefrey and Ladan, Magaji and Shalauddin, Md and Mehmood, Muhammad Shahid (2018) Fabrication of platinum nitrogen-doped graphene nanocomposite modified electrode for the electrochemical detection of acetaminophen. Sensors and Actuators B: Chemical, 266. pp. 375-383. ISSN 0925-4005, DOI https://doi.org/10.1016/j.snb.2018.03.138.
Full text not available from this repository.Abstract
An electrochemical sensor for the determination of acetaminophen (AC) was fabricated on glassy carbon electrode (GCE) modified with platinum nitrogen-doped graphene (Pt/NGr) nanocomposite. Electrochemical impedance spectroscopy (EIS), cyclic voltammetry (CV) and square-wave voltammetry (SWV) were performed to investigate the electrochemical behaviour of AC. From the electrochemical results, the synergy between platinum nanoparticles and nitrogen-doped graphene improved the interfacial electron transfer process, thus exhibited a higher catalytic performance towards the electrochemical oxidation of AC. A linear range between 0.05–90 μmol L−1 for the determination of AC was achieved with a limit of detection of 0.008 μmol L−1. The prepared sensor demonstrated acceptable reproducibility, stability and good selectivity in the presence of interferences such as ascorbic acid, p-aminophenol and dopamine. In addition, this method showed satisfactory results in commercial tablets.
| Item Type: | Article |
|---|---|
| Funders: | University of Malaya under Postgraduate Research Grant (PPP) PG093-2015B and FP039 2106 |
| Uncontrolled Keywords: | Acetaminophen; Electrochemical sensor; Graphene; Platinum nanoparticles |
| Subjects: | Q Science > Q Science (General) Q Science > QC Physics Q Science > QD Chemistry |
| Divisions: | Faculty of Science > Department of Chemistry Faculty of Science > Department of Physics Deputy Vice Chancellor (Research & Innovation) Office > Nanotechnology & Catalysis Research Centre |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 20 Sep 2019 02:49 |
| Last Modified: | 20 Sep 2019 02:49 |
| URI: | http://eprints.um.edu.my/id/eprint/22464 |
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