Prevalence of oral cancer, oral potentially malignant disorders and other oral mucosal lesions in Cambodia

Chher, Tepirou and Hak, Sithan and Kallarakkal, Thomas George and Durward, Callum and Ramanathan, Anand and Ghani, Wan Maria Nabillah Wan Abdul and Razak, Ishak Abdul and Harun, Masitah Hayati and Ashar, Nor Atika Md and Rajandram, Rama Krsna and Prak, Pisethraingsey and Hussaini, Haizal Mohd and Zain, R.B. (2018) Prevalence of oral cancer, oral potentially malignant disorders and other oral mucosal lesions in Cambodia. Ethnicity & Health, 23 (1). pp. 1-15. ISSN 1355-7858, DOI https://doi.org/10.1080/13557858.2016.1246431.

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Official URL: https://doi.org/10.1080/13557858.2016.1246431

Abstract

Objectives: To obtain data on the prevalence of oral mucosal lesions (OMLs) among Cambodians, and to assess the relationship between known risk habits of oral diseases with prevalence of oral potentially malignant disorders (OPMDs). Design: This was a population-based, cross-sectional study whereby subjects were adults aged 18 years old and above. A workshop on the identification of OML was held to train and calibrate dental officers prior to data collection in the field. Sociodemographic and risk habits data were collected via face-to-face interview, whilst presence of OML and clinical details of lesions such as type and site were collected following clinical oral examination by the examiners. Data analysis was carried out using the Statistical Package for Social Science (SPSS) version 12.0. The association between risk habits and risk of OPMD was explored using logistic regression analysis. Results: A total of 1634 subjects were recruited. Prevalence of OML for this population was 54.1%. Linea alba was the most common lesion seen (28.7%). This study showed an overall OPMD prevalence of 5.6%. The most common type of OPMD was leukoplakia (64.8%), followed by lichen planus (30.8%). Subjects who only smoked were found to have an increased risk for OPMD of almost four-fold (RR 3.74, 95%CI 1.89–7.41). The highest risk was found for betel quid chewers, where the increased risk observed was more than six times (RR 6.75, 95%CI 3.32–13.72). Alcohol consumption on its own did not seem to confer an increased risk for OPMD, however when practiced concurrently with smoking, a significant risk of more than five times was noted (RR 5.69 95%CI 3.14–10.29). Conclusion: The prevalence of OML was 54.1%, with linea alba being the most commonly occurring lesion. Smoking, alcohol consumption and betel quid chewing were found to be associated with the prevalence of OPMD, which was 5.6%.

Item Type: Article
Funders: UNSPECIFIED
Uncontrolled Keywords: Oral mucosal lesions; oral cancer; oral potentially malignant disorders; prevalence; Cambodians
Subjects: R Medicine > RK Dentistry
Divisions: Faculty of Dentistry
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 04 Sep 2019 07:19
Last Modified: 04 Sep 2019 07:19
URI: http://eprints.um.edu.my/id/eprint/22224

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