Temperature-induced three-phase equilibrium of medium-chain-length poly-3-hydroxyalkanoates-incorporated emulsion system for production of polymeric nanoparticle

Ishak, Khairul Anwar and Annuar, Mohamad Suffian Mohamad (2018) Temperature-induced three-phase equilibrium of medium-chain-length poly-3-hydroxyalkanoates-incorporated emulsion system for production of polymeric nanoparticle. Journal of Dispersion Science and Technology, 39 (3). pp. 375-383. ISSN 0193-2691, DOI https://doi.org/10.1080/01932691.2017.1320563.

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Official URL: https://doi.org/10.1080/01932691.2017.1320563

Abstract

The study investigated the effects of temperature on the phase behavior of medium-chain-length poly-3-hydroxyalkanoates (mcl-PHA)-incorporated emulsion system. It is suggested that the three-phase equilibrium consisting of lamellar liquid crystalline (La), bi-continuous microemulsion (D), and oil-swollen micelle phases formed in the vicinity of optimal formulation when the combination of phase inversion composition (PIC) and phase inversion temperature (PIT) methods was applied. The interaction effects between two parameters, viz. temperature and mcl-PHA molecular weight, influenced the lamellar/bi-continuous microemulsion formation within the mcl-PHA-incorporated emulsion. It is suggested that the lamellar/bi-continuous microemulsion phase of mcl-PHA-incorporated emulsion can be thermally induced from multiple emulsion system proximately before EIP, and its hypothetical formation mechanism is elucidated in this study.

Item Type: Article
Funders: UNSPECIFIED
Uncontrolled Keywords: Biodegradable polymer; medium-chain-length poly-3-hydroxyalkanoates; phase inversion emulsification; polymeric nanoparticle
Subjects: Q Science > Q Science (General)
Q Science > QH Natural history
Divisions: Faculty of Science > Institute of Biological Sciences
Deputy Vice Chancellor (Research & Innovation) Office > Centre for Research in Biotechnology for Agriculture
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 06 Aug 2019 01:37
Last Modified: 06 Aug 2019 01:37
URI: http://eprints.um.edu.my/id/eprint/21802

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