Jiamsakul, Awachana and Lee, Man Po and Nguyen, Kinh Van and Merati, Tuti Parwati and Cuong, Do Duy and Ditangco, Rossana and Yunihastuti, Evy and Ponnampalavanar, Sasheela and Zhang, Fujie and Kiertiburanakul, Sasisopin and Avihingasanon, Anchalee and Ng, Oon Tek and Sim, Benedict Lim Heng and Wong, Wing Wai and Ross, Jeremy and Law, Matthew (2018) Socio-economic status and risk of tuberculosis: a case-control study of HIV-infected patients in Asia. The International Journal of Tuberculosis and Lung Disease, 22 (2). pp. 179-186. ISSN 1027-3719, DOI https://doi.org/10.5588/ijtld.17.0348.
Full text not available from this repository.Abstract
SETTING: Tuberculosis (TB) is the most common human immunodeficiency virus (HIV) related opportunistic infection and cause of acquired immune-deficiency syndrome related death. TB often affects those from a low socio-economic background. OBJECTIVE : To assess the socio-economic determinants of TB in HIV-infected patients in Asia. DESIGN: This was a matched case-control study. HIVpositive, TB-positive cases were matched to HIVpositive, TB-negative controls according to age, sex and CD4 cell count. A socio-economic questionnaire comprising 23 questions, including education level, employment, housing and substance use, was distributed. Socio-economic risk factors for TB were analysed using conditional logistic regression analysis. RESULT S : A total of 340 patients (170 matched pairs) were recruited, with 262 (77.1%) matched for all three criteria. Pulmonary TB was the predominant type (n = 115, 67.6%). The main risk factor for TB was not having a university level education (OR 4.45, 95%CI 1.50-13.17, P=0.007). Burning wood or coal regularly inside the house and living in the same place of origin were weakly associated with TB diagnosis. CONCLUS IONS : These data suggest that lower socioeconomic status is associated with an increased risk of TB in Asia. Integrating clinical and socio-economic factors into HIV treatment may help in the prevention of opportunistic infections and disease progression.
| Item Type: | Article |
|---|---|
| Funders: | UNSPECIFIED |
| Uncontrolled Keywords: | HIV; Matched; Questionnaire; Socio-economic; TB |
| Subjects: | R Medicine |
| Divisions: | Faculty of Medicine |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 02 Aug 2019 01:30 |
| Last Modified: | 02 Aug 2019 01:30 |
| URI: | http://eprints.um.edu.my/id/eprint/21739 |
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