Incidence of methicillin resistant Staphylococcus aureus (MRSA) in burn intensive care unit: a systematic review

Khan, Tahir Mehmood and Kok, Yee Leng and Bukhsh, Allah and Lee, Learn Han and Chan, Kok Gan and Goh, Bey Hing (2018) Incidence of methicillin resistant Staphylococcus aureus (MRSA) in burn intensive care unit: a systematic review. Germs, 8 (3). pp. 113-125. ISSN 2248-2997

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Official URL: https://doi.org/10.18683/germs.2018.1138

Abstract

Background Burn victims admitted in burn intensive care units (ICU) are at a high risk of nosocomial infections generated by methicillin resistant Staphylococcus aureus (MRSA). This systematic review aims to estimate the incidence of MRSA among burn patients admitted to the ICU setting, with an emphasis on the incidence rate and antibiotic resistance profile of the MRSA strains. Methods A systematic literature search was performed in five electronic databases limited to publication dates from 1 st January 2000 until 31 st August 2017. After screening n=481 articles, n=21 were found to meet the inclusion criteria of this systematic review. Results Results from the meta-analysis revealed that the risk for MRSA isolates in the burn ICU was 55.0% higher (OR 0.55, 95%CI 0.32-0.94). Therefore, timely testing, appropriate hygiene practice and suggested wound care must be practiced while handling such patients. Conclusion Further studies are needed to identify the risk factors of MRSA infections among burn patients and to develop new antimicrobial agents for MRSA infections.

Item Type: Article
Uncontrolled Keywords: Antibiotic resistant; Burn; Meta-analysis; Methicillin resistant staphylococcus aureus (MRSA); Systematic review
Subjects: Q Science > Q Science (General)
Q Science > QH Natural history
Divisions: Faculty of Science > Institute of Biological Sciences
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 15 Jul 2019 05:20
Last Modified: 15 Jul 2019 05:20
URI: http://eprints.um.edu.my/id/eprint/21619

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