Recent strategies to improve boron dipyrromethene (BODIPY) for photodynamic cancer therapy: an updated review

Kue, Chin Siang and Ng, Shie Yin and Voon, Siew Hui and Kamkaew, Anyanee and Chung, Lip Yong and Kiew, Lik Voon and Lee, Hong Boon (2018) Recent strategies to improve boron dipyrromethene (BODIPY) for photodynamic cancer therapy: an updated review. Photochemical & Photobiological Sciences, 17 (11). pp. 1691-1708. ISSN 1474-905X

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Official URL: https://doi.org/10.1039/C8PP00113H

Abstract

BODIPYs are photosensitizers activatable by light to generate highly reactive singlet oxygen (1O2) from molecular oxygen, leading to tissue damage in the photoirradiated region. Despite their extraordinary photophysical characteristics, they are not featured in clinical photodynamic therapy. This review discusses the recent advances in the design and/or modifications of BODIPYs since 2013, to improve their potential in photodynamic cancer therapy and related areas.

Item Type: Article
Uncontrolled Keywords: Antineoplastic Agents; Boron Compounds; Humans; Neoplasms; Photochemotherapy; Photosensitizing Agents
Subjects: R Medicine
Divisions: Faculty of Medicine
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 04 Jul 2019 08:52
Last Modified: 04 Jul 2019 08:52
URI: http://eprints.um.edu.my/id/eprint/21576

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