Cycloartane Triterpenoids with Anti-melanin Deposition Activity

Nugroho, Alfarius Eko and Matsumoto, Misaki and Sotozono, Yayoi and Kaneda, Toshio and Hadi, A. Hamid A. and Morita, Hiroshi (2018) Cycloartane Triterpenoids with Anti-melanin Deposition Activity. Natural Product Communications, 13 (7). pp. 809-812. ISSN 1934-578X

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Official URL: https://doi.org/10.1177/1934578X1801300706

Abstract

Bioactivity guided separation of the extract of Malaysian Garcinia sp. resulted in the isolation of 23-acetoxy-mangiferonic acid (1) and the absolute configuration of C-23 was elucidated to be R by the advanced Mosher's method. The anti-melanin deposition activity of 1 was caused by the down regulation of tyrosinase gene expression.

Item Type: Article
Uncontrolled Keywords: Garcinia; Triterpenoids; Cycloartane; 23-Acetoxy-mangiferonic acid; Anti-melanin deposition activity
Subjects: Q Science > Q Science (General)
Q Science > QD Chemistry
Divisions: Faculty of Science > Dept of Chemistry
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 30 Apr 2019 01:44
Last Modified: 30 Apr 2019 01:44
URI: http://eprints.um.edu.my/id/eprint/21095

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