Rejab, M. and Wong, Jeannie Hsiu Ding and Jamalludin, Zulaikha and Jong, Wei Loong and Malik, Rozita Abdul and Ishak, Wan Zamaniah Wan and Ung, Ngie Min (2018) Dosimetric characterisation of the optically-stimulated luminescence dosimeter in cobalt-60 high dose rate brachytherapy system. Australasian Physical & Engineering Sciences in Medicine, 41 (2). pp. 475-485. ISSN 0158-9938, DOI https://doi.org/10.1007/s13246-018-0647-6.
Full text not available from this repository.Abstract
This study investigates the characteristics and application of the optically-stimulated luminescence dosimeter (OSLD) in cobalt-60 high dose rate (HDR) brachytherapy, and compares the results with the dosage produced by the treatment planning system (TPS). The OSLD characteristics comprised linearity, reproducibility, angular dependence, depth dependence, signal depletion, bleaching rate and cumulative dose measurement. A phantom verification exercise was also conducted using the Farmer ionisation chamber and in vivo diodes. The OSLD signal indicated a supralinear response (R2 = 0.9998). It exhibited a depth-independent trend after a steep dose gradient region. The signal depletion per readout was negligible (0.02%), with expected deviation for angular dependence due to off-axis sensitive volume, ranging from 1 to 16%. The residual signal of the OSLDs after 1 day bleached was within 1.5%. The accumulated and bleached OSLD signals had a standard deviation of ± 0.78 and ± 0.18 Gy, respectively. The TPS was found to underestimate the measured doses with deviations of 5% in OSLD, 17% in the Farmer ionisation chamber, and 7 and 8% for bladder and rectal diode probes. Discrepancies can be due to the positional uncertainty in the high-dose gradient. This demonstrates a slight displacement of the organ at risk near the steep dose gradient region will result in a large dose uncertainty. This justifies the importance of in vivo measurements in cobalt-60 HDR brachytherapy.
| Item Type: | Article |
|---|---|
| Funders: | Malaysian Ministry of Higher Education (UM.C/625/1/HIR/MOHE/MED/38), University of Malaya Postgraduate Research Fund PPP (Grant Number PO026-2015B) |
| Uncontrolled Keywords: | Co-60 HDR brachytherapy; In vivo dosimetry; Optically stimulated luminescent dosimeters |
| Subjects: | R Medicine |
| Divisions: | Faculty of Medicine |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 10 Apr 2019 08:00 |
| Last Modified: | 10 Apr 2019 08:00 |
| URI: | http://eprints.um.edu.my/id/eprint/20895 |
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