Facile Synthesis of N-Phenyl Benzamidine Derivatives, Their Skin Protecting, and Anti-Aging Activity

Taj, M.B. and Tirmizi, Syed Ahmed and Raheel, Ahmad and Alelwani, W. and Hajjar, D. and Makki, Arwa A. and Ali, U. and Darroudi, Majid and Ali, Hapipah Mohd (2018) Facile Synthesis of N-Phenyl Benzamidine Derivatives, Their Skin Protecting, and Anti-Aging Activity. Russian Journal of General Chemistry, 88 (11). pp. 2425-2431. ISSN 1070-3632

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Official URL: https://doi.org/10.1134/S1070363218110270

Abstract

The straight forwarded new green approach to the synthesis of N-phenyl benzamidine derivatives catalyzed by copper oxide nanoparticles (CuO np ) under solvent-free conditions (without microwave radiations and with MW radiation) is presented. All synthesized compounds 3a–3k are characterized by FT-IR, NMR, and single crystal XRD analysis and tested for their antioxidant and elastase inhibition activities. The compounds 3i and 3j demonstrate significant free radical scavenging activity. The accumulated data indicate that some synthesized compounds can be recognized as good anti-aging agents.

Item Type: Article
Uncontrolled Keywords: antioxidant activity; elastase inhibition; MW radiations; N-phenyl benzamidine; SFRC
Subjects: Q Science > Q Science (General)
Q Science > QD Chemistry
Divisions: Faculty of Science > Dept of Chemistry
Depositing User: Ms. Juhaida Abd Rahim
Date Deposited: 04 Mar 2019 04:23
Last Modified: 04 Mar 2019 04:23
URI: http://eprints.um.edu.my/id/eprint/20572

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