Tan, Li Kuo and McLaughlin, Robert A. and Lim, Einly and Abdul Aziz, Yang Faridah and Liew, Yih Miin (2018) Fully automated segmentation of the left ventricle in cine cardiac MRI using neural network regression. Journal of Magnetic Resonance Imaging, 48 (1). pp. 140-152. ISSN 1053-1807, DOI https://doi.org/10.1002/jmri.25932.
Full text not available from this repository.Abstract
Background: Left ventricle (LV) structure and functions are the primary assessment performed in most clinical cardiac MRI protocols. Fully automated LV segmentation might improve the efficiency and reproducibility of clinical assessment. Purpose: To develop and validate a fully automated neural network regression-based algorithm for segmentation of the LV in cardiac MRI, with full coverage from apex to base across all cardiac phases, utilizing both short axis (SA) and long axis (LA) scans. Study Type: Cross-sectional survey; diagnostic accuracy. Subjects: In all, 200 subjects with coronary artery diseases and regional wall motion abnormalities from the public 2011 Left Ventricle Segmentation Challenge (LVSC) database; 1140 subjects with a mix of normal and abnormal cardiac functions from the public Kaggle Second Annual Data Science Bowl database. Field Strength/Sequence: 1.5T, steady-state free precession. Assessment: Reference standard data generated by experienced cardiac radiologists. Quantitative measurement and comparison via Jaccard and Dice index, modified Hausdorff distance (MHD), and blood volume. Statistical Tests: Paired t-tests compared to previous work. Results: Tested against the LVSC database, we obtained 0.77 ± 0.11 (Jaccard index) and 1.33 ± 0.71 mm (MHD), both metrics demonstrating statistically significant improvement (P < 0.001) compared to previous work. Tested against the Kaggle database, the signed difference in evaluated blood volume was +7.2 ± 13.0 mL and –19.8 ± 18.8 mL for the end-systolic (ES) and end-diastolic (ED) phases, respectively, with a statistically significant improvement (P < 0.001) for the ED phase. Data Conclusion: A fully automated LV segmentation algorithm was developed and validated against a diverse set of cardiac cine MRI data sourced from multiple imaging centers and scanner types. The strong performance overall is suggestive of practical clinical utility. Level of Evidence: 3. Technical Efficacy: Stage 2. J. Magn. Reson. Imaging 2018.
| Item Type: | Article |
|---|---|
| Funders: | Contract grant sponsor: University of Malaya Research Grant; contract grant number: RP028A/B/C-14HTM, Contract grant sponsor: Ministry of Higher Education (MOHE), Malaysia, Fundamental Research Grant Scheme (FRGS); contract grant number: FP002-2017, Premier’s Research and Industry Fund grant provided by the South Australian Government Department of State Development, Australian Research Council, grant no(s). CE140100003 and DP150104660 |
| Uncontrolled Keywords: | automated segmentation; cardiac MRI; cine MRI; deep learning; LV segmentation |
| Subjects: | R Medicine |
| Divisions: | Faculty of Engineering Faculty of Medicine |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 28 Feb 2019 05:08 |
| Last Modified: | 28 Feb 2019 05:08 |
| URI: | http://eprints.um.edu.my/id/eprint/20534 |
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