Tunna, Tasnuva Sarwar and Sarker, Md. Zaidul Islam and Ghafoor, Kashif and Ferdosh, Sahena and Jaffri, Juliana Md and Al-Juhaimi, Fahad Y and Ali, Md. Eaqub and Akanda, Md. Jahurul Haque and Awal, Md Shihabul and Ahmed, Qamar Uddin and Selamat, Jinap (2018) Enrichment, in vitro, and quantification study of antidiabetic compounds from neglected weed Mimosa pudica using supercritical CO2 and CO2-Soxhlet. Separation Science and Technology, 53 (2). pp. 243-260. ISSN 0149-6395, DOI https://doi.org/10.1080/01496395.2017.1384015.
Full text not available from this repository.Abstract
Supercritical fluid extraction (SFE) using carbon dioxide (CO2) and liquid CO2 using Soxhlet (CO2-Soxhlet) extraction were employed to extract three (3) antidiabetic compounds viz. stigmasterol, quercetin, and avicularin from Mimosa pudica. Various extraction parameters were studied. Extracts were analyzed pharmacologically, qualitatively and quantitatively to ascertain enrichment levels. All three antidiabetic compounds were effectively enriched under optimized conditions of temperature 60°C, pressure 40 MPa, co-solvent ratio 30%, and CO2 flow rate of 5 ml min−1. SFE was found to be the better method for enrichment of the antidiabetic compounds than the CO2-Soxhlet method. Extraction conditions were seen to affect the enrichment of desired compounds.
| Item Type: | Article |
|---|---|
| Funders: | The exploratory research grant scheme, no. ERGS13-028-0061 of Ministry of Higher Education, Malaysia, International Scientific Partnership Program (ISPP) at King Saud University, Riyadh, Saudi Arabia: ISPP# 0026, Research Initiative Grant Scheme (RIGS16-303-0467) of International Islamic University Malaysia |
| Uncontrolled Keywords: | Mimosa pudica; supercritical fluid extraction (SFE); CO2-Soxhlet; antidiabetic compounds; α-glucosidase assay |
| Subjects: | Q Science > Q Science (General) Q Science > QD Chemistry |
| Divisions: | Nanotechnology & Catalysis Research Centre |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 22 Feb 2019 08:22 |
| Last Modified: | 22 Feb 2019 08:22 |
| URI: | http://eprints.um.edu.my/id/eprint/20450 |
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