Wan Ab Naim, Wan Naimah and Ganesan, Poo Balan and Sun, Zhonghua and Lei, Jing and Jansen, Shirley and Hashim, Shahrul Amry and Ho, Teik Kok and Lim, Einly (2018) Flow pattern analysis in type B aortic dissection patients after stent-grafting repair: Comparison between complete and incomplete false lumen thrombosis. International Journal for Numerical Methods in Biomedical Engineering, 34 (5). e2961. ISSN 2040-7939, DOI https://doi.org/10.1002/cnm.2961.
Full text not available from this repository.Abstract
Endovascular stent graft repair has become a common treatment for complicated Stanford type B aortic dissection to restore true lumen flow and induce false lumen thrombosis. Using computational fluid dynamics, this study reports the differences in flow patterns and wall shear stress distribution in complicated Stanford type B aortic dissection patients after endovascular stent graft repair. Five patients were included in this study: 2 have more than 80% false lumen thrombosis (group 1), while 3 others had less than 80% false lumen thrombosis (group 2) within 1 year following endovascular repair. Group 1 patients had concentrated re-entry tears around the abdominal branches only, while group 2 patients had re-entry tears that spread along the dissection line. Blood flow inside the false lumen which affected thrombus formation increased with the number of re-entry tears and when only small amounts of blood that entered the false lumen exited through the branches. In those cases where dissection extended below the abdominal branches (group 2), patients with fewer re-entry tears and longer distance between the tears had low wall shear stress contributing to thrombosis. This work provides an insight into predicting the development of complete or incomplete false lumen thrombosis and has implications for patient selection for treatment.
| Item Type: | Article |
|---|---|
| Funders: | Royal Society‐Newton Advanced Fellowship grant |
| Uncontrolled Keywords: | aortic dissection; computational fluid dynamics; endovascular stent graft repair; false lumen; thrombosis |
| Subjects: | R Medicine T Technology > TJ Mechanical engineering and machinery |
| Divisions: | Faculty of Engineering Faculty of Medicine |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 21 Feb 2019 02:50 |
| Last Modified: | 21 Feb 2019 02:50 |
| URI: | http://eprints.um.edu.my/id/eprint/20412 |
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