Obaid Aldulaimi, Ahmed Kareem and Abdul Azziz, Saripah Salbiah Syed and Bakri, Yuhanis Mhd and Nafiah, Mohd Azlan and Aowda, Saadon Abdulla and Awang, Khalijah and Litaudon, Marc (2019) Two New isoquinoline alkaloids from the bark of Alphonsea cylindrica King and their antioxidant activity. Phytochemistry Letters, 29. pp. 110-114. ISSN 1874-3900, DOI https://doi.org/10.1016/j.phytol.2018.11.022.
Full text not available from this repository.Abstract
Two new isoquinoline alkaloids, iraqiine (1) and kareemine (2), along with five known alkaloids, muniranine (3), kinabaline (4), O-methylmoschatoline (5), atherospermidine (6) and N-methylouregidione (7), were purified from the dichloromethane crude extract of Alphonsea cylindrica bark. The structures of these compounds were elucidated through extensive 1D and 2D NMR, IR and LC–MS studies and comparison with previously reported data. Compounds (1–5 and 7) were tested for their antioxidant activity using in vitro DPPH radical scavenging assay, and 1, 3 and 4 showed the highest antioxidant activities with IC50 values of 48.77 ± 1.01, 44.51 ± 1.12 and 64.28 ± 0.93 μg/ml, respectively.
| Item Type: | Article |
|---|---|
| Funders: | Universiti Pendidikan Sultan Idris Special Grant Scheme (Fundamental) 2017-0331-101-01 |
| Uncontrolled Keywords: | Alphonsea cylindrical; Isoquinoline; Oxoaporphine; Bisbenzylisoquinoline; DPPH |
| Subjects: | Q Science > Q Science (General) Q Science > QD Chemistry |
| Divisions: | Faculty of Science > Department of Chemistry |
| Depositing User: | Ms. Juhaida Abd Rahim |
| Date Deposited: | 17 Jan 2019 01:06 |
| Last Modified: | 17 Jan 2019 01:06 |
| URI: | http://eprints.um.edu.my/id/eprint/20016 |
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